This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4bs5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (07:17, 1 May 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4bs5| PDB=4bs5 | SCENE= }}
 
-
===MOUSE CATHEPSIN S WITH COVALENT LIGAND===
 
-
{{ABSTRACT_PUBMED_24224654}}
 
-
==Function==
+
==MOUSE CATHEPSIN S WITH COVALENT LIGAND==
-
[[http://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
+
<StructureSection load='4bs5' size='340' side='right'caption='[[4bs5]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[4bs5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BS5 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG2:(2S,4R)-N-[1-(IMINOMETHYL)CYCLOPROPYL]-4-[2-(TRIFLUOROMETHYL)PHENYL]SULFONYL-PYRROLIDINE-2-CARBOXAMIDE'>MG2</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bs5 OCA], [https://pdbe.org/4bs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bs5 RCSB], [https://www.ebi.ac.uk/pdbsum/4bs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bs5 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CATS_MOUSE CATS_MOUSE] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
-
==About this Structure==
+
==See Also==
-
[[4bs5]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BS5 OCA].
+
*[[Cathepsin 3D structures|Cathepsin 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:024224654</ref><references group="xtra"/><references/>
+
[[Category: Large Structures]]
-
[[Category: Cathepsin S]]
+
[[Category: Mus musculus]]
-
[[Category: Banner, D W.]]
+
[[Category: Banner DW]]
-
[[Category: Benz, J.]]
+
[[Category: Benz J]]
-
[[Category: Gsell, B.]]
+
[[Category: Gsell B]]
-
[[Category: Haap, W.]]
+
[[Category: Haap W]]
-
[[Category: Ruf, A.]]
+
[[Category: Ruf A]]
-
[[Category: Stihle, M.]]
+
[[Category: Stihle M]]
-
[[Category: Covalent ligand]]
+
-
[[Category: Cysteine protease]]
+
-
[[Category: Hydrolase]]
+

Current revision

MOUSE CATHEPSIN S WITH COVALENT LIGAND

PDB ID 4bs5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4bs5"
Personal tools