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4c0k
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| - | {{STRUCTURE_4c0k| PDB=4c0k | SCENE= }} | ||
| - | ===Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one calcium ion (Ca-MiroS)=== | ||
| - | {{ABSTRACT_PUBMED_24071720}} | ||
| - | == | + | ==Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one calcium ion (Ca-MiroS)== |
| - | [[http://www.uniprot.org/uniprot/MIRO_DROME MIRO_DROME | + | <StructureSection load='4c0k' size='340' side='right'caption='[[4c0k]], [[Resolution|resolution]] 2.80Å' scene=''> |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4c0k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C0K FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HSE:L-HOMOSERINE'>HSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c0k OCA], [https://pdbe.org/4c0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c0k RCSB], [https://www.ebi.ac.uk/pdbsum/4c0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c0k ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MIRO_DROME MIRO_DROME] Mitochondrial GTPase involved in mitochondrial trafficking. Milt and Miro form an essential protein complex that links Khc to mitochondria for light chain-independent, anterograde transport of mitochondria. Required for axonal transport to synapses within nerve terminals. Required presynaptically but not postsynaptically at neuromuscular junctions (NMJs).<ref>PMID:16055062</ref> <ref>PMID:16717129</ref> | ||
| - | == | + | ==See Also== |
| - | [[ | + | *[[Rho GTPase 3D structures|Rho GTPase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
| - | [[Category: Chakravarthy | + | [[Category: Large Structures]] |
| - | [[Category: Focia | + | [[Category: Chakravarthy S]] |
| - | [[Category: Freymann | + | [[Category: Focia PJ]] |
| - | [[Category: Klosowiak | + | [[Category: Freymann DM]] |
| - | [[Category: Landahl | + | [[Category: Klosowiak JL]] |
| - | [[Category: Rice | + | [[Category: Landahl EC]] |
| - | [[Category: Wawrzak | + | [[Category: Rice SE]] |
| - | + | [[Category: Wawrzak Z]] | |
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Current revision
Crystal structure of Drosophila Miro EF hand and cGTPase domains bound to one calcium ion (Ca-MiroS)
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