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5ej0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5ej0 is ON HOLD until Paper Publication Authors: Singh, K., Gittis, A.G., Gitti, R.K., Ostazesky, S.A., Su, H.P., Garboczi, D.N. Description: [[Ca...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose== |
| - | + | <StructureSection load='5ej0' size='340' side='right'caption='[[5ej0]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5ej0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_WR Vaccinia virus WR]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EJ0 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHL:2-AMINO-ETHANETHIOL'>DHL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MOH:METHANOL'>MOH</scene>, <scene name='pdbligand=PDO:1,3-PROPANDIOL'>PDO</scene>, <scene name='pdbligand=PG0:2-(2-METHOXYETHOXY)ETHANOL'>PG0</scene>, <scene name='pdbligand=POL:N-PROPANOL'>POL</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ej0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ej0 OCA], [https://pdbe.org/5ej0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ej0 RCSB], [https://www.ebi.ac.uk/pdbsum/5ej0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ej0 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/H3_VACCW H3_VACCW] Envelope protein that binds to heparan sulfate on the cell surface and might provide virion attachment to target cell.<ref>PMID:10708453</ref> <ref>PMID:2462305</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: Singh | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus WR]] | ||
| + | [[Category: Garboczi DN]] | ||
| + | [[Category: Gitti RK]] | ||
| + | [[Category: Gittis AG]] | ||
| + | [[Category: Ostazesky SA]] | ||
| + | [[Category: Singh K]] | ||
| + | [[Category: Su HP]] | ||
Current revision
The vaccinia virus H3 envelope protein, a major target of neutralizing antibodies, exhibits a glycosyltransferase fold and binds UDP-Glucose
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