This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5hlz
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5hlz is ON HOLD Authors: Wang, X., Fischer, G., Hyvonen, M. Description: Category: Unreleased Structures Category: Hyvonen, M [[Category: ...) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Pro-Activin A Complex at 2.85 A resolution== | |
| + | <StructureSection load='5hlz' size='340' side='right'caption='[[5hlz]], [[Resolution|resolution]] 2.85Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5hlz]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HLZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HLZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.851Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hlz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hlz OCA], [https://pdbe.org/5hlz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hlz RCSB], [https://www.ebi.ac.uk/pdbsum/5hlz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hlz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INHBA_HUMAN INHBA_HUMAN] Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. | ||
| - | + | ==See Also== | |
| - | + | *[[Activin|Activin]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Fischer G]] |
| + | [[Category: Hyvonen M]] | ||
| + | [[Category: Wang X]] | ||
Current revision
Structure of Pro-Activin A Complex at 2.85 A resolution
| |||||||||||
