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6yyp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6yyp is ON HOLD Authors: Wagener, M., Schade, M., Merla, B., Hars, U., Kueckelhaus, S.Q. Description: Structure of Cathepsin S in complex with Comp...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Cathepsin S in complex with Compound 2== | |
| + | <StructureSection load='6yyp' size='340' side='right'caption='[[6yyp]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6yyp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6YYP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6YYP FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=Q1H:1-(furan-2-ylmethyl)-5-(trifluoromethyl)benzimidazol-2-amine'>Q1H</scene>, <scene name='pdbligand=SIN:SUCCINIC+ACID'>SIN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6yyp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6yyp OCA], [https://pdbe.org/6yyp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6yyp RCSB], [https://www.ebi.ac.uk/pdbsum/6yyp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6yyp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N. | ||
| - | + | ==See Also== | |
| - | + | *[[Cathepsin 3D structures|Cathepsin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Merla | + | [[Category: Hars U]] |
| - | [[Category: | + | [[Category: Kueckelhaus SQ]] |
| - | [[Category: | + | [[Category: Merla B]] |
| + | [[Category: Schade M]] | ||
| + | [[Category: Wagener M]] | ||
Current revision
Structure of Cathepsin S in complex with Compound 2
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