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6zqd

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Current revision (07:42, 1 May 2024) (edit) (undo)
 
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====
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==Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1==
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<StructureSection load='6zqd' size='340' side='right'caption='[[6zqd]]' scene=''>
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<StructureSection load='6zqd' size='340' side='right'caption='[[6zqd]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6zqd]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ZQD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ZQD FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6zqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zqd OCA], [http://pdbe.org/6zqd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6zqd RCSB], [http://www.ebi.ac.uk/pdbsum/6zqd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6zqd ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6zqd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6zqd OCA], [https://pdbe.org/6zqd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6zqd RCSB], [https://www.ebi.ac.uk/pdbsum/6zqd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6zqd ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/UTP8_YEAST UTP8_YEAST] Involved in nucleolar processing of pre-18S ribosomal RNA. Also has a role in nuclear tRNA export. It acts between the steps of tRNA maturation/aminoacylation and its subsequent translocation out of the nucleus. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs).<ref>PMID:12068309</ref> <ref>PMID:12794079</ref> <ref>PMID:15489292</ref>
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==See Also==
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*[[Adenosine dimethyltransferase 3D structures|Adenosine dimethyltransferase 3D structures]]
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*[[Ribosome 3D structures|Ribosome 3D structures]]
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*[[Ribosome biogenesis protein 3D structures|Ribosome biogenesis protein 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Beckmann R]]
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[[Category: Berninghausen O]]
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[[Category: Cheng J]]
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[[Category: Hurt E]]
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[[Category: Lau B]]
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[[Category: Venuta GL]]

Current revision

Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Post-A1

PDB ID 6zqd

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