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7abh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7abh is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)== | |
| + | <StructureSection load='7abh' size='340' side='right'caption='[[7abh]], [[Resolution|resolution]] 4.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7abh]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ABH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ABH FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7abh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7abh OCA], [https://pdbe.org/7abh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7abh RCSB], [https://www.ebi.ac.uk/pdbsum/7abh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7abh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CDC5L_HUMAN CDC5L_HUMAN] Note=A chromosomal aberration involving CDC5L is found in multicystic renal dysplasia. Translocation t(6;19)(p21;q13.1) with USF2. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CDC5L_HUMAN CDC5L_HUMAN] DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.<ref>PMID:9038199</ref> <ref>PMID:9632794</ref> <ref>PMID:9468527</ref> <ref>PMID:10570151</ref> <ref>PMID:11101529</ref> <ref>PMID:11082045</ref> <ref>PMID:11544257</ref> <ref>PMID:12927788</ref> <ref>PMID:18583928</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Bertram K]] | ||
| + | [[Category: Kastner B]] | ||
| + | [[Category: Leelaram MN]] | ||
| + | [[Category: Luehrmann R]] | ||
| + | [[Category: Stark H]] | ||
| + | [[Category: Townsend C]] | ||
Current revision
Human pre-Bact-2 spliceosome (SF3b/U2 snRNP portion)
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