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7bht

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==Crystal structure of MAT2a with quinazolinone fragment 5 bound in the allosteric site==
==Crystal structure of MAT2a with quinazolinone fragment 5 bound in the allosteric site==
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<StructureSection load='7bht' size='340' side='right'caption='[[7bht]]' scene=''>
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<StructureSection load='7bht' size='340' side='right'caption='[[7bht]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BHT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7bht]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BHT FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bht OCA], [https://pdbe.org/7bht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bht RCSB], [https://www.ebi.ac.uk/pdbsum/7bht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bht ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.052&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene>, <scene name='pdbligand=TO8:7-chloranyl-4-(dimethylamino)-1~{H}-quinazolin-2-one'>TO8</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bht OCA], [https://pdbe.org/7bht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bht RCSB], [https://www.ebi.ac.uk/pdbsum/7bht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bht ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/METK2_HUMAN METK2_HUMAN] Catalyzes the formation of S-adenosylmethionine from methionine and ATP.
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==See Also==
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*[[S-adenosylmethionine synthetase 3D structures|S-adenosylmethionine synthetase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Argyrou A]]
[[Category: Argyrou A]]

Current revision

Crystal structure of MAT2a with quinazolinone fragment 5 bound in the allosteric site

PDB ID 7bht

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