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7bj2

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Current revision (07:48, 1 May 2024) (edit) (undo)
 
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<StructureSection load='7bj2' size='340' side='right'caption='[[7bj2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='7bj2' size='340' side='right'caption='[[7bj2]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7bj2]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BJ2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7bj2]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BJ2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BJ2 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bj2 OCA], [https://pdbe.org/7bj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bj2 RCSB], [https://www.ebi.ac.uk/pdbsum/7bj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bj2 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bj2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bj2 OCA], [https://pdbe.org/7bj2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bj2 RCSB], [https://www.ebi.ac.uk/pdbsum/7bj2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bj2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FLGI_SALTY FLGI_SALTY]] Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
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[https://www.uniprot.org/uniprot/FLGI_SALTY FLGI_SALTY] Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The bacterial flagellum is a macromolecular protein complex that enables motility in many species. Bacterial flagella self-assemble a strong, multicomponent drive shaft that couples rotation in the inner membrane to the micrometre-long flagellar filament that powers bacterial swimming in viscous fluids(1-3). Here, we present structures of the intact Salmonella flagellar basal body(4), encompassing the inner membrane rotor, drive shaft and outer-membrane bushing, solved using cryo-electron microscopy to resolutions of 2.2-3.7 A. The structures reveal molecular details of how 173 protein molecules of 13 different types assemble into a complex spanning two membranes and a cell wall. The helical drive shaft at one end is intricately interwoven with the rotor component with both the export gate complex and the proximal rod forming interactions with the MS-ring. At the other end, the drive shaft distal rod passes through the LP-ring bushing complex, which functions as a molecular bearing anchored in the outer membrane through interactions with the lipopolysaccharide. The in situ structure of a protein complex capping the drive shaft provides molecular insights into the assembly process of this molecular machine.
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Molecular structure of the intact bacterial flagellar basal body.,Johnson S, Furlong EJ, Deme JC, Nord AL, Caesar JJE, Chevance FFV, Berry RM, Hughes KT, Lea SM Nat Microbiol. 2021 Apr 30. pii: 10.1038/s41564-021-00895-y. doi:, 10.1038/s41564-021-00895-y. PMID:33931760<ref>PMID:33931760</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 7bj2" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Salty]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
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[[Category: Furlong, E]]
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[[Category: Furlong E]]
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[[Category: Johnson, S]]
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[[Category: Johnson S]]
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[[Category: Lea, S M]]
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[[Category: Lea SM]]
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[[Category: Bacterial flagellum rod bacterial flagellum export gate basal body]]
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[[Category: Protein transport]]
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Current revision

Salmonella flagellar basal body assembly intermediate - P ring alone structure

PDB ID 7bj2

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