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1rhg

From Proteopedia

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{{Seed}}
 
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[[Image:1rhg.png|left|200px]]
 
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==THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS==
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The line below this paragraph, containing "STRUCTURE_1rhg", creates the "Structure Box" on the page.
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<StructureSection load='1rhg' size='340' side='right'caption='[[1rhg]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rhg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RHG FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rhg OCA], [https://pdbe.org/1rhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rhg RCSB], [https://www.ebi.ac.uk/pdbsum/1rhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rhg ProSAT]</span></td></tr>
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{{STRUCTURE_1rhg| PDB=1rhg | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CSF3_HUMAN CSF3_HUMAN] Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/1rhg_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rhg ConSurf].
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<div style="clear:both"></div>
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===THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS===
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==See Also==
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*[[Colony-stimulating factor 3D structures|Colony-stimulating factor 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_7685117}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 7685117 is the PubMed ID number.
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{{ABSTRACT_PUBMED_7685117}}
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==About this Structure==
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1RHG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHG OCA].
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==Reference==
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The structure of granulocyte-colony-stimulating factor and its relationship to other growth factors., Hill CP, Osslund TD, Eisenberg D, Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5167-71. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7685117 7685117]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Eisenberg, D.]]
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[[Category: Eisenberg D]]
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[[Category: Hill, C P.]]
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[[Category: Hill CP]]
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[[Category: Osslund, T D.]]
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[[Category: Osslund TD]]
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[[Category: Growth factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 20:08:40 2008''
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Current revision

THE STRUCTURE OF GRANULOCYTE-COLONY-STIMULATING FACTOR AND ITS RELATIONSHIP TO THOSE OF OTHER GROWTH FACTORS

PDB ID 1rhg

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