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1rl5
From Proteopedia
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| - | [[Image:1rl5.png|left|200px]] | ||
| - | + | ==NMR structure with tightly bound water molecule of cytotoxin I from Naja oxiana in aqueous solution (major form)== | |
| - | + | <StructureSection load='1rl5' size='340' side='right'caption='[[1rl5]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1rl5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RL5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RL5 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rl5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rl5 OCA], [https://pdbe.org/1rl5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rl5 RCSB], [https://www.ebi.ac.uk/pdbsum/1rl5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rl5 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | [[1rl5]] is a 1 chain structure with sequence from [ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/3SA1_NAJOX 3SA1_NAJOX] This three-finger cytotoxin is a basic protein that interacts and penetrates into the cell membrane, with the tips of all the three loops. Cytotoxins which have a 'Pro-30' (P-type) interacts with membrane stronger that those which have a Ser-28 (S-type). CTI interacts with membrane weaker than CTII. | |
| - | == | + | == Evolutionary Conservation == |
| - | < | + | [[Image:Consurf_key_small.gif|200px|right]] |
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/1rl5_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rl5 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Naja oxiana]] | [[Category: Naja oxiana]] | ||
| - | [[Category: Arseniev | + | [[Category: Arseniev AS]] |
| - | [[Category: Dubinnyi | + | [[Category: Dubinnyi MA]] |
| - | [[Category: Dubovskii | + | [[Category: Dubovskii PV]] |
| - | [[Category: Pustovalova | + | [[Category: Pustovalova YE]] |
| - | [[Category: Utkin | + | [[Category: Utkin YN]] |
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Current revision
NMR structure with tightly bound water molecule of cytotoxin I from Naja oxiana in aqueous solution (major form)
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