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1rlr

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{{Seed}}
 
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[[Image:1rlr.png|left|200px]]
 
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==STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1==
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The line below this paragraph, containing "STRUCTURE_1rlr", creates the "Structure Box" on the page.
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<StructureSection load='1rlr' size='340' side='right'caption='[[1rlr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rlr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RLR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RLR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rlr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rlr OCA], [https://pdbe.org/1rlr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rlr RCSB], [https://www.ebi.ac.uk/pdbsum/1rlr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rlr ProSAT]</span></td></tr>
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{{STRUCTURE_1rlr| PDB=1rlr | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RIR1_ECOLI RIR1_ECOLI] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rl/1rlr_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rlr ConSurf].
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<div style="clear:both"></div>
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===STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1===
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==See Also==
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*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_8052308}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 8052308 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8052308}}
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==About this Structure==
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1RLR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RLR OCA].
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==Reference==
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Structure of ribonucleotide reductase protein R1., Uhlin U, Eklund H, Nature. 1994 Aug 18;370(6490):533-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8052308 8052308]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Ribonucleoside-diphosphate reductase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Eklund H]]
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[[Category: Eklund, H.]]
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[[Category: Uhlin U]]
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[[Category: Uhlin, U.]]
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[[Category: Oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 00:34:30 2008''
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Current revision

STRUCTURE OF RIBONUCLEOTIDE REDUCTASE PROTEIN R1

PDB ID 1rlr

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