This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1rsr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:26, 1 May 2024) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1rsr.gif|left|200px]]
 
-
{{Structure
+
==azide complex of the diferrous F208A mutant R2 subunit of ribonucleotide reductase==
-
|PDB= 1rsr |SIZE=350|CAPTION= <scene name='initialview01'>1rsr</scene>, resolution 2.00&Aring;
+
<StructureSection load='1rsr' size='340' side='right'caption='[[1rsr]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene> and <scene name='pdbligand=AZI:AZIDE ION'>AZI</scene>
+
<table><tr><td colspan='2'>[[1rsr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RSR FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
|GENE=
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZI:AZIDE+ION'>AZI</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
-
}}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rsr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rsr OCA], [https://pdbe.org/1rsr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rsr RCSB], [https://www.ebi.ac.uk/pdbsum/1rsr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rsr ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rs/1rsr_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rsr ConSurf].
 +
<div style="clear:both"></div>
-
'''azide complex of the diferrous F208A mutant R2 subunit of ribonucleotide reductase'''
+
==See Also==
-
 
+
*[[Ribonucleotide reductase 3D structures|Ribonucleotide reductase 3D structures]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
1RSR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RSR OCA].
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Ribonucleoside-diphosphate reductase]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Andersson KK]]
-
[[Category: Andersson, K K.]]
+
[[Category: Andersson ME]]
-
[[Category: Andersson, M E.]]
+
[[Category: Hogbom M]]
-
[[Category: Hogbom, M.]]
+
[[Category: Nordlund P]]
-
[[Category: Nordlund, P.]]
+
[[Category: Rinaldo-Matthis A]]
-
[[Category: Rinaldo-Matthis, A.]]
+
[[Category: Sjoberg BM]]
-
[[Category: Sjoberg, B M.]]
+
-
[[Category: AZI]]
+
-
[[Category: FE2]]
+
-
[[Category: HG]]
+
-
[[Category: azide]]
+
-
[[Category: diiron]]
+
-
[[Category: oxygen activation]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:55:40 2008''
+

Current revision

azide complex of the diferrous F208A mutant R2 subunit of ribonucleotide reductase

PDB ID 1rsr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rsr"
Personal tools