This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ru5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:27, 1 May 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1ru5.png|left|200px]]
 
-
<!--
+
==Solution structure of porcine peptide YY (pPYY)==
-
The line below this paragraph, containing "STRUCTURE_1ru5", creates the "Structure Box" on the page.
+
<StructureSection load='1ru5' size='340' side='right'caption='[[1ru5]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1ru5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RU5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RU5 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-
{{STRUCTURE_1ru5| PDB=1ru5 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ru5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ru5 OCA], [https://pdbe.org/1ru5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ru5 RCSB], [https://www.ebi.ac.uk/pdbsum/1ru5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ru5 ProSAT]</span></td></tr>
-
 
+
</table>
-
===Solution structure of porcine peptide YY (pPYY)===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/PYY_PIG PYY_PIG] This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.
-
 
+
== Evolutionary Conservation ==
-
<!--
+
[[Image:Consurf_key_small.gif|200px|right]]
-
The line below this paragraph, {{ABSTRACT_PUBMED_15178255}}, adds the Publication Abstract to the page
+
Check<jmol>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15178255 is the PubMed ID number.
+
<jmolCheckbox>
-
-->
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ru/1ru5_consurf.spt"</scriptWhenChecked>
-
{{ABSTRACT_PUBMED_15178255}}
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
 
+
<text>to colour the structure by Evolutionary Conservation</text>
-
==About this Structure==
+
</jmolCheckbox>
-
1RU5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RU5 OCA].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ru5 ConSurf].
-
 
+
<div style="clear:both"></div>
-
==Reference==
+
__TOC__
-
Structural similarities of micelle-bound peptide YY (PYY) and neuropeptide Y (NPY) are related to their affinity profiles at the Y receptors., Lerch M, Mayrhofer M, Zerbe O, J Mol Biol. 2004 Jun 18;339(5):1153-68. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15178255 15178255]
+
</StructureSection>
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
-
[[Category: Lerch, M.]]
+
[[Category: Lerch M]]
-
[[Category: Mayrhofer, M.]]
+
[[Category: Mayrhofer M]]
-
[[Category: Zerbe, O.]]
+
[[Category: Zerbe O]]
-
[[Category: Alpha-helical]]
+
-
[[Category: Pp-fold]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:06:25 2008''
+

Current revision

Solution structure of porcine peptide YY (pPYY)

PDB ID 1ru5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools