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1rw1

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[[Image:1rw1.gif|left|200px]]
 
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==YFFB (PA3664) PROTEIN==
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The line below this paragraph, containing "STRUCTURE_1rw1", creates the "Structure Box" on the page.
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<StructureSection load='1rw1' size='340' side='right'caption='[[1rw1]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RW1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.02&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_1rw1| PDB=1rw1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rw1 OCA], [https://pdbe.org/1rw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rw1 RCSB], [https://www.ebi.ac.uk/pdbsum/1rw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rw1 ProSAT]</span></td></tr>
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</table>
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'''YFFB (PA3664) PROTEIN'''
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== Function ==
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[https://www.uniprot.org/uniprot/Q9HXX5_PSEAE Q9HXX5_PSEAE]
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== Evolutionary Conservation ==
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==Overview==
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[[Image:Consurf_key_small.gif|200px|right]]
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BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein. RESULTS: The structure was determined at 1.0 A resolution by single-wavelength anomalous diffraction. The fold is very similar to that of arsenate reductase, which is an extension of the thioredoxin fold. CONCLUSION: Given the conservation of the functionally important residues and the ability to bind glutathione, YffB is likely to function as a GSH-dependent thiol reductase.
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rw/1rw1_consurf.spt"</scriptWhenChecked>
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1RW1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15102337 15102337]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rw1 ConSurf].
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[[Category: Pseudomonas aeruginosa pao1]]
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<div style="clear:both"></div>
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[[Category: Single protein]]
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__TOC__
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[[Category: Dauter, M.]]
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</StructureSection>
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[[Category: Dauter, Z.]]
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[[Category: Large Structures]]
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[[Category: Doseeva, V.]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Galkin, A.]]
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[[Category: Dauter M]]
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[[Category: Gilliland, G L.]]
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[[Category: Dauter Z]]
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[[Category: Herzberg, O.]]
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[[Category: Doseeva V]]
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[[Category: Obmolova, G.]]
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[[Category: Galkin A]]
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[[Category: Pullalarevu, S.]]
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[[Category: Gilliland GL]]
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Herzberg O]]
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[[Category: Teplyakov, A.]]
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[[Category: Obmolova G]]
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[[Category: S2f]]
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[[Category: Pullalarevu S]]
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[[Category: Structural genomic]]
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[[Category: Teplyakov A]]
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[[Category: Structure 2 function project]]
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[[Category: Thioredoxin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:58:22 2008''
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Current revision

YFFB (PA3664) PROTEIN

PDB ID 1rw1

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