This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1rw1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="1rw1" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rw1, resolution 1.02&Aring;" /> '''YFFB (PA3664) PROTEI...)
Current revision (08:27, 1 May 2024) (edit) (undo)
 
(14 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1rw1.gif|left|200px]]<br /><applet load="1rw1" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1rw1, resolution 1.02&Aring;" />
 
-
'''YFFB (PA3664) PROTEIN'''<br />
 
-
==Overview==
+
==YFFB (PA3664) PROTEIN==
-
BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an, uncharacterized protein of 13 kDa molecular weight with a marginal, sequence similarity to arsenate reductase from Escherichia coli. The, crystal structure determination of YffB was undertaken as part of a, structural genomics effort in order to assist with the functional, assignment of the protein. RESULTS: The structure was determined at 1.0 A, resolution by single-wavelength anomalous diffraction. The fold is very, similar to that of arsenate reductase, which is an extension of the, thioredoxin fold. CONCLUSION: Given the conservation of the functionally, important residues and the ability to bind glutathione, YffB is likely to, function as a GSH-dependent thiol reductase.
+
<StructureSection load='1rw1' size='340' side='right'caption='[[1rw1]], [[Resolution|resolution]] 1.02&Aring;' scene=''>
-
 
+
== Structural highlights ==
-
==About this Structure==
+
<table><tr><td colspan='2'>[[1rw1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RW1 FirstGlance]. <br>
-
1RW1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1] with IPA as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RW1 OCA].
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.02&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-
==Reference==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rw1 OCA], [https://pdbe.org/1rw1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rw1 RCSB], [https://www.ebi.ac.uk/pdbsum/1rw1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rw1 ProSAT]</span></td></tr>
-
Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15102337 15102337]
+
</table>
-
[[Category: Pseudomonas aeruginosa pao1]]
+
== Function ==
-
[[Category: Single protein]]
+
[https://www.uniprot.org/uniprot/Q9HXX5_PSEAE Q9HXX5_PSEAE]
-
[[Category: Dauter, M.]]
+
== Evolutionary Conservation ==
-
[[Category: Dauter, Z.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Doseeva, V.]]
+
Check<jmol>
-
[[Category: Galkin, A.]]
+
<jmolCheckbox>
-
[[Category: Gilliland, G.L.]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rw/1rw1_consurf.spt"</scriptWhenChecked>
-
[[Category: Herzberg, O.]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: Obmolova, G.]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: Pullalarevu, S.]]
+
</jmolCheckbox>
-
[[Category: S2F, Structure.2.Function.Project.]]
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rw1 ConSurf].
-
[[Category: Teplyakov, A.]]
+
<div style="clear:both"></div>
-
[[Category: IPA]]
+
__TOC__
-
[[Category: s2f]]
+
</StructureSection>
-
[[Category: structural genomics]]
+
[[Category: Large Structures]]
-
[[Category: structure 2 function project]]
+
[[Category: Pseudomonas aeruginosa PAO1]]
-
[[Category: thioredoxin fold]]
+
[[Category: Dauter M]]
-
 
+
[[Category: Dauter Z]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 23:23:13 2007''
+
[[Category: Doseeva V]]
 +
[[Category: Galkin A]]
 +
[[Category: Gilliland GL]]
 +
[[Category: Herzberg O]]
 +
[[Category: Obmolova G]]
 +
[[Category: Pullalarevu S]]
 +
[[Category: Teplyakov A]]

Current revision

YFFB (PA3664) PROTEIN

PDB ID 1rw1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1rw1"
Personal tools