This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1s4n

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1s4n" [edit=sysop:move=sysop])
Current revision (08:28, 1 May 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1s4n.png|left|200px]]
 
-
{{STRUCTURE_1s4n| PDB=1s4n | SCENE= }}
+
==Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p==
-
 
+
<StructureSection load='1s4n' size='340' side='right'caption='[[1s4n]], [[Resolution|resolution]] 2.01&Aring;' scene=''>
-
===Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1s4n]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S4N FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_14752117}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s4n OCA], [https://pdbe.org/1s4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s4n RCSB], [https://www.ebi.ac.uk/pdbsum/1s4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s4n ProSAT]</span></td></tr>
-
[[1s4n]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S4N OCA].
+
</table>
-
 
+
== Function ==
-
==Reference==
+
[https://www.uniprot.org/uniprot/KRE2_YEAST KRE2_YEAST] Required for the attachment of the third mannose residue of O-linked saccharides.
-
<ref group="xtra">PMID:014752117</ref><references group="xtra"/>
+
== Evolutionary Conservation ==
-
[[Category: Glycolipid 2-alpha-mannosyltransferase]]
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/s4/1s4n_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1s4n ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Herscovics, A.]]
+
[[Category: Herscovics A]]
-
[[Category: Howell, P L.]]
+
[[Category: Howell PL]]
-
[[Category: Lobsanov, Y D.]]
+
[[Category: Lobsanov YD]]
-
[[Category: Romero, P A.]]
+
[[Category: Romero PA]]
-
[[Category: Sleno, B.]]
+
[[Category: Sleno B]]
-
[[Category: Yip, P.]]
+
[[Category: Yip P]]
-
[[Category: Yu, B.]]
+
[[Category: Yu B]]
-
[[Category: Alpha/beta fold]]
+
-
[[Category: Nucleotide-binding domain]]
+
-
[[Category: Rossmann fold]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of yeast alpha1,2-mannosyltransferase Kre2p/Mnt1p

PDB ID 1s4n

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools