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1sez

From Proteopedia

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[[Image:1sez.png|left|200px]]
 
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{{STRUCTURE_1sez| PDB=1sez | SCENE= }}
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==Crystal Structure of Protoporphyrinogen IX Oxidase==
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<StructureSection load='1sez' size='340' side='right'caption='[[1sez]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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===Crystal Structure of Protoporphyrinogen IX Oxidase===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1sez]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SEZ FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15057273}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=OMN:4-BROMO-3-(5-CARBOXY-4-CHLORO-2-FLUOROPHENYL)-1-METHYL-5-TRIFLUOROMETHYL-PYRAZOL'>OMN</scene>, <scene name='pdbligand=TON:2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL'>TON</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sez OCA], [https://pdbe.org/1sez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sez RCSB], [https://www.ebi.ac.uk/pdbsum/1sez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sez ProSAT]</span></td></tr>
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[[1sez]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEZ OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/PPOM_TOBAC PPOM_TOBAC] Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.<ref>PMID:9238074</ref> Provides precursor for the mitochondrial and plastidic heme synthesis and the predominant chlorophyll synthesis in plastids.<ref>PMID:9238074</ref>
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<ref group="xtra">PMID:015057273</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/se/1sez_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sez ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Nicotiana tabacum]]
[[Category: Nicotiana tabacum]]
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[[Category: Protoporphyrinogen oxidase]]
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[[Category: Breithaupt C]]
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[[Category: Breithaupt, C.]]
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[[Category: Freigang J]]
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[[Category: Freigang, J.]]
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[[Category: Huber R]]
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[[Category: Huber, R.]]
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[[Category: Kiefersauer R]]
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[[Category: Kiefersauer, R.]]
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[[Category: Koch M]]
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[[Category: Koch, M.]]
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[[Category: Messerschmidt A]]
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[[Category: Messerschmidt, A.]]
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[[Category: Fad-binding]]
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[[Category: Monotopic membrane-binding domain]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal Structure of Protoporphyrinogen IX Oxidase

PDB ID 1sez

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