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1sfp
From Proteopedia
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| - | [[Image:1sfp.gif|left|200px]]<br /><applet load="1sfp" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1sfp, resolution 1.90Å" /> | ||
| - | '''CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY'''<br /> | ||
| - | == | + | ==CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY== |
| - | + | <StructureSection load='1sfp' size='340' side='right'caption='[[1sfp]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[1sfp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFP FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfp OCA], [https://pdbe.org/1sfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sfp RCSB], [https://www.ebi.ac.uk/pdbsum/1sfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sfp ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | + | == Function == | |
| + | [https://www.uniprot.org/uniprot/SPAD1_BOVIN SPAD1_BOVIN] Stimulates cell division and progesterone secretion of bovine granulosa cells in vitro in a potent and dose dependent manner. This protein appears to be a potent growth factor with effects on ovarian granulosa cells. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sfp_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sfp ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Calvete | + | [[Category: Calvete JJ]] |
| - | [[Category: Carvalho | + | [[Category: Carvalho AL]] |
| - | [[Category: Dias | + | [[Category: Dias JM]] |
| - | [[Category: Kolln | + | [[Category: Kolln I]] |
| - | [[Category: Romao | + | [[Category: Romao MJ]] |
| - | [[Category: Romero | + | [[Category: Romero A]] |
| - | [[Category: Sanz | + | [[Category: Sanz L]] |
| - | [[Category: Topfer-Petersen | + | [[Category: Topfer-Petersen E]] |
| - | [[Category: Varela | + | [[Category: Varela PF]] |
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Current revision
CRYSTAL STRUCTURE OF ACIDIC SEMINAL FLUID PROTEIN (ASFP) AT 1.9 A RESOLUTION: A BOVINE POLYPEPTIDE FROM THE SPERMADHESIN FAMILY
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Categories: Bos taurus | Large Structures | Calvete JJ | Carvalho AL | Dias JM | Kolln I | Romao MJ | Romero A | Sanz L | Topfer-Petersen E | Varela PF
