1spk

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[[Image:1spk.gif|left|200px]]<br /><applet load="1spk" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1spk" />
 
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'''Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA'''<br />
 
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==About this Structure==
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==Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA==
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1SPK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SPK OCA].
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<StructureSection load='1spk' size='340' side='right'caption='[[1spk]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1spk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SPK FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1spk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1spk OCA], [https://pdbe.org/1spk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1spk RCSB], [https://www.ebi.ac.uk/pdbsum/1spk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1spk ProSAT], [https://www.topsan.org/Proteins/RSGI/1spk TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BI2L1_MOUSE BI2L1_MOUSE] May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sp/1spk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1spk ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Abe T]]
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[[Category: Abe, T.]]
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[[Category: Hayashi F]]
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[[Category: Hayashi, F.]]
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[[Category: Hirota H]]
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[[Category: Hirota, H.]]
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[[Category: Suzuki Y]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Suzuki, Y.]]
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[[Category: Yokoyama, S.]]
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[[Category: five-stranded barrel]]
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[[Category: mouse cdna]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: sh3 domain]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:03:52 2008''
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Current revision

Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA

PDB ID 1spk

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