1spk
From Proteopedia
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==Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA== | ==Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA== | ||
- | <StructureSection load='1spk' size='340' side='right' caption='[[1spk | + | <StructureSection load='1spk' size='340' side='right'caption='[[1spk]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1spk]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1spk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SPK FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1spk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1spk OCA], [https://pdbe.org/1spk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1spk RCSB], [https://www.ebi.ac.uk/pdbsum/1spk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1spk ProSAT], [https://www.topsan.org/Proteins/RSGI/1spk TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/BI2L1_MOUSE BI2L1_MOUSE] May function as adapter protein. Involved in the formation of clusters of actin bundles. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
- | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sp/1spk_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sp/1spk_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
- | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1spk ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: | + | [[Category: Mus musculus]] |
- | [[Category: | + | [[Category: Abe T]] |
- | [[Category: | + | [[Category: Hayashi F]] |
- | [[Category: | + | [[Category: Hirota H]] |
- | [[Category: Suzuki | + | [[Category: Suzuki Y]] |
- | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
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Current revision
Solution Structure of RSGI RUH-010, an SH3 Domain from Mouse cDNA
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Categories: Large Structures | Mus musculus | Abe T | Hayashi F | Hirota H | Suzuki Y | Yokoyama S