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1sqv

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{{Seed}}
 
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[[Image:1sqv.png|left|200px]]
 
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==Crystal Structure Analysis of Bovine Bc1 with UHDBT==
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The line below this paragraph, containing "STRUCTURE_1sqv", creates the "Structure Box" on the page.
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<StructureSection load='1sqv' size='340' side='right'caption='[[1sqv]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1sqv]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SQV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=UHD:6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE'>UHD</scene>, <scene name='pdbligand=UQ2:UBIQUINONE-2'>UQ2</scene></td></tr>
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{{STRUCTURE_1sqv| PDB=1sqv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sqv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sqv OCA], [https://pdbe.org/1sqv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sqv RCSB], [https://www.ebi.ac.uk/pdbsum/1sqv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sqv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/QCR1_BOVIN QCR1_BOVIN] This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sq/1sqv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sqv ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure Analysis of Bovine Bc1 with UHDBT===
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==See Also==
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*[[Cytochrome C 3D structures|Cytochrome C 3D structures]]
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*[[Cytochrome bc1 3D structures|Cytochrome bc1 3D structures]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_15312779}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 15312779 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15312779}}
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==About this Structure==
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1SQV is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SQV OCA].
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==Reference==
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Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex., Esser L, Quinn B, Li YF, Zhang M, Elberry M, Yu L, Yu CA, Xia D, J Mol Biol. 2004 Jul 30;341(1):281-302. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15312779 15312779]
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Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria., Xia D, Yu CA, Kim H, Xia JZ, Kachurin AM, Zhang L, Yu L, Deisenhofer J, Science. 1997 Jul 4;277(5322):60-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9204897 9204897]
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The crystal structure of mitochondrial cytochrome bc1 in complex with famoxadone: the role of aromatic-aromatic interaction in inhibition., Gao X, Wen X, Yu C, Esser L, Tsao S, Quinn B, Zhang L, Yu L, Xia D, Biochemistry. 2002 Oct 1;41(39):11692-702. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12269811 12269811]
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[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Ubiquinol--cytochrome-c reductase]]
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[[Category: Elberry M]]
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[[Category: Elberry, M.]]
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[[Category: Esser L]]
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[[Category: Esser, L.]]
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[[Category: Li YF]]
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[[Category: Li, Y F.]]
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[[Category: Quinn B]]
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[[Category: Quinn, B.]]
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[[Category: Xia D]]
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[[Category: Xia, D.]]
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[[Category: Yu CA]]
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[[Category: Yu, C A.]]
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[[Category: Yu L]]
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[[Category: Yu, L.]]
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[[Category: Zhang M]]
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[[Category: Zhang, M.]]
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[[Category: Cytochrome bc1]]
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[[Category: Electron transport]]
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[[Category: Membrane protein]]
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[[Category: Qo inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 12:39:03 2008''
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Current revision

Crystal Structure Analysis of Bovine Bc1 with UHDBT

PDB ID 1sqv

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