This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ssu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1ssu" [edit=sysop:move=sysop])
Current revision (08:35, 1 May 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ssu.png|left|200px]]
 
-
{{STRUCTURE_1ssu| PDB=1ssu | SCENE= }}
+
==Structural and biochemical evidence for disulfide bond heterogeneity in active forms of the somatomedin B domain of human vitronectin==
-
 
+
<StructureSection load='1ssu' size='340' side='right'caption='[[1ssu]]' scene=''>
-
===Structural and biochemical evidence for disulfide bond heterogeneity in active forms of the somatomedin B domain of human vitronectin===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[1ssu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SSU FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_15157085}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
 
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ssu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ssu OCA], [https://pdbe.org/1ssu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ssu RCSB], [https://www.ebi.ac.uk/pdbsum/1ssu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ssu ProSAT]</span></td></tr>
-
==About this Structure==
+
</table>
-
[[1ssu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSU OCA].
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/VTNC_HUMAN VTNC_HUMAN] Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
-
==Reference==
+
== Evolutionary Conservation ==
-
<ref group="xtra">PMID:015157085</ref><references group="xtra"/>
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ss/1ssu_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ssu ConSurf].
 +
<div style="clear:both"></div>
 +
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Churchill, M J.]]
+
[[Category: Large Structures]]
-
[[Category: Curriden, S.]]
+
[[Category: Churchill MJ]]
-
[[Category: Dawson, P.]]
+
[[Category: Curriden S]]
-
[[Category: Dyson, H J.]]
+
[[Category: Dawson P]]
-
[[Category: Guzman, R De.]]
+
[[Category: De Guzman R]]
-
[[Category: Jagielska, A.]]
+
[[Category: Dyson HJ]]
-
[[Category: Kamikubo, Y.]]
+
[[Category: Jagielska A]]
-
[[Category: Kroon, G.]]
+
[[Category: Kamikubo Y]]
-
[[Category: Loskutoff, D J.]]
+
[[Category: Kroon G]]
-
[[Category: Neels, J G.]]
+
[[Category: Loskutoff DJ]]
-
[[Category: Oldziej, S.]]
+
[[Category: Neels JG]]
-
[[Category: Scheraga, H A.]]
+
[[Category: Oldziej S]]
-
[[Category: Cell adhesion]]
+
[[Category: Scheraga HA]]
-
[[Category: Disulfide bonds heterogeneity]]
+
-
[[Category: Somatostatin b domain]]
+
-
[[Category: Vitronectin]]
+

Current revision

Structural and biochemical evidence for disulfide bond heterogeneity in active forms of the somatomedin B domain of human vitronectin

PDB ID 1ssu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ssu"
Personal tools