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1sza

From Proteopedia

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[[Image:1sza.png|left|200px]]
 
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{{STRUCTURE_1sza| PDB=1sza | SCENE= }}
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==The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model==
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<StructureSection load='1sza' size='340' side='right'caption='[[1sza]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1sza]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZA FirstGlance]. <br>
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{{ABSTRACT_PUBMED_15241417}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sza OCA], [https://pdbe.org/1sza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sza RCSB], [https://www.ebi.ac.uk/pdbsum/1sza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sza ProSAT]</span></td></tr>
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[[1sza]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZA OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/PCF11_YEAST PCF11_YEAST] Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factor NAB4/CFIB and the cleavage and polyadenylation factor (CPF) complex. Independently involved in RNA polymerase II transcript termination. Binds RNA. Seems to bridge RNA polymerase II and the native transcript and may be involved in dismantling the RNA polymerase II elongation complex.<ref>PMID:11344258</ref> <ref>PMID:15998810</ref>
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<ref group="xtra">PMID:015241417</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1sza_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sza ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cramer, P.]]
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[[Category: Cramer P]]
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[[Category: Meinhart, A.]]
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[[Category: Meinhart A]]
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[[Category: Arm repeat]]
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[[Category: Pcf11]]
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[[Category: Phosphoserine]]
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[[Category: Rna polymerase ii ctd interacting domain]]
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[[Category: Transcription]]
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Current revision

The RNA polymerase II CTD in mRNA processing: beta-turn recognition and beta-spiral model

PDB ID 1sza

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