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1szs

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[[Image:1szs.png|left|200px]]
 
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{{STRUCTURE_1szs| PDB=1szs | SCENE= }}
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==The structure of gamma-aminobutyrate aminotransferase mutant: I50Q==
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<StructureSection load='1szs' size='340' side='right'caption='[[1szs]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1szs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SZS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PMP:4-DEOXY-4-AMINOPYRIDOXAL-5-PHOSPHATE'>PMP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1szs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1szs OCA], [https://pdbe.org/1szs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1szs RCSB], [https://www.ebi.ac.uk/pdbsum/1szs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1szs ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GABT_ECOLI GABT_ECOLI] Catalyzes the transfer of the amino group from gamma-aminobutyrate (GABA) to alpha-ketoglutarate (KG) to yield succinic semialdehyde (SSA).<ref>PMID:20639325</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sz/1szs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1szs ConSurf].
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<div style="clear:both"></div>
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===The structure of gamma-aminobutyrate aminotransferase mutant: I50Q===
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==See Also==
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*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
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{{ABSTRACT_PUBMED_15723541}}
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== References ==
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<references/>
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==About this Structure==
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__TOC__
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[[1szs]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SZS OCA].
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</StructureSection>
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==Reference==
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<ref group="xtra">PMID:015723541</ref><references group="xtra"/>
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[[Category: 4-aminobutyrate transaminase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Fisher, A J.]]
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[[Category: Large Structures]]
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[[Category: Jin, X.]]
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[[Category: Fisher AJ]]
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[[Category: Langston, J A.]]
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[[Category: Jin X]]
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[[Category: Liu, W.]]
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[[Category: Langston JA]]
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[[Category: Peterson, P E.]]
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[[Category: Liu W]]
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[[Category: Toney, M D.]]
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[[Category: Peterson PE]]
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[[Category: Zhou, X.]]
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[[Category: Toney MD]]
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[[Category: Gaba-at]]
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[[Category: Zhou X]]
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[[Category: Transferase]]
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Current revision

The structure of gamma-aminobutyrate aminotransferase mutant: I50Q

PDB ID 1szs

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