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1t5y
From Proteopedia
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| - | [[Image:1t5y.png|left|200px]] | ||
| - | + | ==Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p== | |
| - | + | <StructureSection load='1t5y' size='340' side='right'caption='[[1t5y]], [[Resolution|resolution]] 2.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1t5y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T5Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | [[1t5y]] is a 1 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t5y OCA], [https://pdbe.org/1t5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t5y RCSB], [https://www.ebi.ac.uk/pdbsum/1t5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t5y ProSAT], [https://www.topsan.org/Proteins/NESGC/1t5y TOPSAN]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NIP7_HUMAN NIP7_HUMAN] Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.<ref>PMID:22195017</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t5/1t5y_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t5y ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Acton | + | [[Category: Large Structures]] |
| - | [[Category: Chen | + | [[Category: Acton TB]] |
| - | [[Category: Cooper | + | [[Category: Chen Y]] |
| - | [[Category: Forouhar | + | [[Category: Cooper B]] |
| - | [[Category: Hunt | + | [[Category: Forouhar F]] |
| - | [[Category: Kuzin | + | [[Category: Hunt JF]] |
| - | [[Category: Ma | + | [[Category: Kuzin AP]] |
| - | [[Category: Montelione | + | [[Category: Ma L-C]] |
| - | + | [[Category: Montelione G]] | |
| - | [[Category: Shastry | + | [[Category: Shastry R]] |
| - | [[Category: Tong | + | [[Category: Tong L]] |
| - | [[Category: Xiao | + | [[Category: Xiao R]] |
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Current revision
Crystal Structure of Northeast Structural Genomics Consortium Target HR2118: A Human Homolog of Saccharomyces cerevisiae Nip7p
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Categories: Homo sapiens | Large Structures | Acton TB | Chen Y | Cooper B | Forouhar F | Hunt JF | Kuzin AP | Ma L-C | Montelione G | Shastry R | Tong L | Xiao R
