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1ta3

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{{Seed}}
 
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[[Image:1ta3.png|left|200px]]
 
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==Crystal Structure of xylanase (GH10) in complex with inhibitor (XIP)==
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The line below this paragraph, containing "STRUCTURE_1ta3", creates the "Structure Box" on the page.
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<StructureSection load='1ta3' size='340' side='right'caption='[[1ta3]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1ta3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aspergillus_nidulans Aspergillus nidulans] and [https://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TA3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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{{STRUCTURE_1ta3| PDB=1ta3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ta3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ta3 OCA], [https://pdbe.org/1ta3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ta3 RCSB], [https://www.ebi.ac.uk/pdbsum/1ta3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ta3 ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of xylanase (GH10) in complex with inhibitor (XIP)===
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== Function ==
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[https://www.uniprot.org/uniprot/XIP1_WHEAT XIP1_WHEAT] Fungal xylanase inhibitor. Possesses competitive inhibiting activity against fungal endo-1,4-beta-D-xylanases belonging to glycoside hydrolase family 10 (GH10) and family 11 (GH11). Possesses also inhibitory activity towards barley alpha-amylases. Binding to xylanases or amylases is necessary for inhibition activity. May function in plant defense against secreted fungal pathogen xylanases. Is similar to class III chitinases, but does not exhibit chitinase activity.<ref>PMID:12023019</ref> <ref>PMID:10024521</ref> <ref>PMID:11955286</ref> <ref>PMID:12922177</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15181003}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15181003 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ta/1ta3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15181003}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1TA3 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Emericella_nidulans Emericella nidulans] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TA3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ta3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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The dual nature of the wheat xylanase protein inhibitor XIP-I: structural basis for the inhibition of family 10 and family 11 xylanases., Payan F, Leone P, Porciero S, Furniss C, Tahir T, Williamson G, Durand A, Manzanares P, Gilbert HJ, Juge N, Roussel A, J Biol Chem. 2004 Aug 20;279(34):36029-37. Epub 2004 Jun 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15181003 15181003]
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<references/>
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[[Category: Emericella nidulans]]
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__TOC__
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[[Category: Endo-1,4-beta-xylanase]]
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</StructureSection>
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[[Category: Protein complex]]
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[[Category: Aspergillus nidulans]]
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[[Category: Large Structures]]
[[Category: Triticum aestivum]]
[[Category: Triticum aestivum]]
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[[Category: Durand, A.]]
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[[Category: Durand A]]
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[[Category: Furniss, C.]]
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[[Category: Furniss C]]
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[[Category: Gilbert, H J.]]
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[[Category: Gilbert HJ]]
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[[Category: Juge, N.]]
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[[Category: Juge N]]
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[[Category: Leone, P.]]
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[[Category: Leone P]]
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[[Category: Manzanares, P.]]
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[[Category: Manzanares P]]
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[[Category: Payan, F.]]
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[[Category: Payan F]]
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[[Category: Porciero, S.]]
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[[Category: Porciero S]]
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[[Category: Roussel, A.]]
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[[Category: Roussel A]]
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[[Category: Tahir, T.]]
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[[Category: Tahir T]]
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[[Category: Williamson, G.]]
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[[Category: Williamson G]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:07:33 2008''
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Current revision

Crystal Structure of xylanase (GH10) in complex with inhibitor (XIP)

PDB ID 1ta3

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