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1tiy

From Proteopedia

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[[Image:1tiy.gif|left|200px]]
 
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{{Structure
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==X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160==
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|PDB= 1tiy |SIZE=350|CAPTION= <scene name='initialview01'>1tiy</scene>, resolution 2.50&Aring;
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<StructureSection load='1tiy' size='340' side='right'caption='[[1tiy]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[1tiy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TIY FirstGlance]. <br>
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Guanine_deaminase Guanine deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.3 3.5.4.3] </span>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE= GUAD, GDE, BSU13170 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01285 nucleoside_deaminase]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tiy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tiy OCA], [https://pdbe.org/1tiy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tiy RCSB], [https://www.ebi.ac.uk/pdbsum/1tiy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tiy ProSAT], [https://www.topsan.org/Proteins/NESGC/1tiy TOPSAN]</span></td></tr>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tiy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tiy OCA], [http://www.ebi.ac.uk/pdbsum/1tiy PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=1tiy RCSB]</span>
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</table>
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}}
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== Function ==
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[https://www.uniprot.org/uniprot/GUAD_BACSU GUAD_BACSU] Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ti/1tiy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tiy ConSurf].
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<div style="clear:both"></div>
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'''X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160'''
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1TIY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TIY OCA].
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Guanine deaminase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Acton T]]
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[[Category: Acton, T.]]
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[[Category: Chiang Y-W]]
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[[Category: Chiang, Y W.]]
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[[Category: Edstrom W]]
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[[Category: Edstrom, W.]]
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[[Category: Forouhar F]]
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[[Category: Forouhar, F.]]
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[[Category: Hunt JF]]
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[[Category: Hunt, J F.]]
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[[Category: Kuzin AP]]
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[[Category: Kuzin, A P.]]
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[[Category: Ma L-C]]
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[[Category: Ma, L C.]]
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[[Category: Montelione G]]
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[[Category: Montelione, G.]]
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[[Category: Shastry R]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Tong L]]
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[[Category: Shastry, R.]]
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[[Category: Vorobiev S]]
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[[Category: Tong, L.]]
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[[Category: Vorobiev, S.]]
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[[Category: nesg]]
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[[Category: northeast structural genomics consortium]]
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[[Category: protein structure initiative]]
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[[Category: protein-zn complex]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:07:24 2008''
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Current revision

X-RAY STRUCTURE OF GUANINE DEAMINASE FROM BACILLUS SUBTILIS NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET SR160

PDB ID 1tiy

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