This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1tof

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:42, 1 May 2024) (edit) (undo)
 
(22 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1tof.gif|left|200px]]<br />
 
-
<applet load="1tof" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="1tof" />
 
-
'''THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES'''<br />
 
-
==Overview==
+
==THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES==
-
NMR solution structures of a cytosolic plant thioredoxin h (112 amino, acids, 11.7 kDa) from the green alga Chlamydonmonas reinhardtii have been, calculated on the basis of 1904 NMR distance restraints, which include 90, distances used to restrain 45 hydrogen bonds, and 44 phi dihedral, restraints. The structure of C. reinhardtii thioredoxin h was solved in, its oxidised form, and the ensemble of 23 converged structures superpose, to the geometric average structure with an atomic rmsd of 0.080 nm +/-, 0.016 for the (N, C(alpha), C) backbone atoms of residues 4-110., Comparisons with other thioredoxins, such as thioredoxin from the, bacterium Escherichia coli, thioredoxin 2 from a cyanobacterium of the, Anabaena genus, and human thioredoxin, showed that thioredoxin h models, share more ... [[http://ispc.weizmann.ac.il/pmbin/getpm?9030762 (full description)]]
+
<StructureSection load='1tof' size='340' side='right'caption='[[1tof]]' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1tof]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TOF FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tof OCA], [https://pdbe.org/1tof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tof RCSB], [https://www.ebi.ac.uk/pdbsum/1tof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tof ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRXH_CHLRE TRXH_CHLRE] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The H form is known to activate a number of cytosolic enzymes.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/to/1tof_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tof ConSurf].
 +
<div style="clear:both"></div>
-
==About this Structure==
+
==See Also==
-
1TOF is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]]. Structure known Active Site: ACT. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1TOF OCA]].
+
*[[Thioredoxin 3D structures|Thioredoxin 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
NMR solution structure of an oxidised thioredoxin h from the eukaryotic green alga Chlamydomonas reinhardtii., Mittard V, Blackledge MJ, Stein M, Jacquot JP, Marion D, Lancelin JM, Eur J Biochem. 1997 Jan 15;243(1-2):374-83. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9030762 9030762]
+
[[Category: Chlamydomonas reinhardtii]]
[[Category: Chlamydomonas reinhardtii]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Blackledge, M.J.]]
+
[[Category: Blackledge MJ]]
-
[[Category: Jacquot, J.P.]]
+
[[Category: Jacquot J-P]]
-
[[Category: Lancelin, J.M.]]
+
[[Category: Lancelin J-M]]
-
[[Category: Marion, D.]]
+
[[Category: Marion D]]
-
[[Category: Mittard, V.]]
+
[[Category: Mittard V]]
-
[[Category: Stein, M.]]
+
[[Category: Stein M]]
-
[[Category: electron transport]]
+
-
[[Category: oxidoreductase]]
+
-
 
+
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 13:53:26 2007''
+

Current revision

THIOREDOXIN H (OXIDIZED FORM), NMR, 23 STRUCTURES

PDB ID 1tof

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1tof"
Personal tools