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1u1z

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{{Seed}}
 
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[[Image:1u1z.png|left|200px]]
 
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<!--
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==The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)==
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The line below this paragraph, containing "STRUCTURE_1u1z", creates the "Structure Box" on the page.
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<StructureSection load='1u1z' size='340' side='right'caption='[[1u1z]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1u1z]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. The June 2007 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Fatty Acid Synthase'' by David S. Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2007_6 10.2210/rcsb_pdb/mom_2007_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U1Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U1Z FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1u1z| PDB=1u1z | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u1z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u1z OCA], [https://pdbe.org/1u1z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u1z RCSB], [https://www.ebi.ac.uk/pdbsum/1u1z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u1z ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABZ_PSEAE FABZ_PSEAE] Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u1/1u1z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u1z ConSurf].
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<div style="clear:both"></div>
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===The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)===
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==See Also==
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*[[Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures|Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15371447}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15371447 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15371447}}
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==About this Structure==
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1U1Z is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. The June 2007 RCSB PDB [http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Fatty Acid Synthase'' by David S. Goodsell is [http://dx.doi.org/10.2210/rcsb_pdb/mom_2007_6 10.2210/rcsb_pdb/mom_2007_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U1Z OCA].
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==Reference==
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<ref group="xtra">PMID:15371447</ref><references group="xtra"/>
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[[Category: Fatty Acid Synthase]]
[[Category: Fatty Acid Synthase]]
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[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: RCSB PDB Molecule of the Month]]
[[Category: RCSB PDB Molecule of the Month]]
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[[Category: Dharamsi, A.]]
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[[Category: Dharamsi A]]
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[[Category: Fiebig, K M.]]
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[[Category: Fiebig KM]]
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[[Category: Houston, S.]]
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[[Category: Houston S]]
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[[Category: Kimber, M S.]]
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[[Category: Kimber MS]]
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[[Category: Lu, Y.]]
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[[Category: Lu Y]]
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[[Category: Martin, F.]]
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[[Category: Martin F]]
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[[Category: Rock, C O.]]
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[[Category: Rock CO]]
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[[Category: Schmid, M.]]
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[[Category: Schmid M]]
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[[Category: Vedadi, M.]]
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[[Category: Vedadi M]]
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[[Category: Dehydratase]]
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[[Category: Fatty acid biosynthesis]]
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[[Category: Hot dog fold]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jan 21 08:38:03 2010''
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Current revision

The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)

PDB ID 1u1z

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