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1u2x

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[[Image:1u2x.png|left|200px]]
 
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{{STRUCTURE_1u2x| PDB=1u2x | SCENE= }}
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==Crystal Structure of a Hypothetical ADP-dependent Phosphofructokinase from Pyrococcus horikoshii OT3==
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<StructureSection load='1u2x' size='340' side='right'caption='[[1u2x]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===Crystal Structure of a Hypothetical ADP-dependent Phosphofructokinase from Pyrococcus horikoshii OT3===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1u2x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U2X FirstGlance]. <br>
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{{ABSTRACT_PUBMED_019553681}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u2x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u2x OCA], [https://pdbe.org/1u2x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u2x RCSB], [https://www.ebi.ac.uk/pdbsum/1u2x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u2x ProSAT]</span></td></tr>
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[[1u2x]] is a 2 chain structure of [[Phosphofructokinase (PFK)]] with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U2X OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/K6PF_PYRHO K6PF_PYRHO] Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u2/1u2x_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u2x ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Phosphofructokinase (PFK)|Phosphofructokinase (PFK)]]
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*[[Phosphofructokinase 3D structures|Phosphofructokinase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019553681</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: ADP-specific phosphofructokinase]]
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[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Arrowsmith, C.]]
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[[Category: Arrowsmith C]]
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[[Category: Edwards, A.]]
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[[Category: Edwards A]]
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[[Category: Jia, Z.]]
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[[Category: Jia Z]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Savchenko A]]
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[[Category: Savchenko, A.]]
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[[Category: Skarina T]]
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[[Category: Skarina, T.]]
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[[Category: Walker JR]]
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[[Category: Walker, J R.]]
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[[Category: Wong AHY]]
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[[Category: Wong, A H.Y.]]
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[[Category: Adp-pfk]]
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[[Category: Apc5054]]
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[[Category: Mcsg]]
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[[Category: Midwest center for structural genomic]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyrococcus]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of a Hypothetical ADP-dependent Phosphofructokinase from Pyrococcus horikoshii OT3

PDB ID 1u2x

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