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8z5l
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8z5l is ON HOLD Authors: Kamo, T., Kuroda, K., Nimura, S., Guo, Y., Kondo, S., Nukaga, M., Hoshino, T. Description: Crystal structure of metallo-be...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor== | |
| - | + | <StructureSection load='8z5l' size='340' side='right'caption='[[8z5l]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8z5l]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=8y0s 8y0s]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z5L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z5L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1LXO:3-[2-azanyl-5-[2-cyclohexylethyl-[3-(4-methylphenoxy)propyl]amino]phenyl]propanoic+acid'>A1LXO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: Guo | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z5l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z5l OCA], [https://pdbe.org/8z5l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z5l RCSB], [https://www.ebi.ac.uk/pdbsum/8z5l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z5l ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/BLAB_SERMA BLAB_SERMA] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Serratia marcescens]] | ||
| + | [[Category: Guo Y]] | ||
| + | [[Category: Hoshino T]] | ||
| + | [[Category: Kamo T]] | ||
| + | [[Category: Kondo S]] | ||
| + | [[Category: Kuroda K]] | ||
| + | [[Category: Nimura S]] | ||
| + | [[Category: Nukaga M]] | ||
Current revision
Crystal structure of metallo-beta-lactamse, IMP-1, complexed with a quinolinone-based inhibitor
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Categories: Large Structures | Serratia marcescens | Guo Y | Hoshino T | Kamo T | Kondo S | Kuroda K | Nimura S | Nukaga M
