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1dwo
From Proteopedia
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<StructureSection load='1dwo' size='340' side='right'caption='[[1dwo]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='1dwo' size='340' side='right'caption='[[1dwo]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1dwo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1dwo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Manihot_esculenta Manihot esculenta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DWO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DWO FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACN:ACETONE'>ACN</scene></td></tr> |
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dwo OCA], [https://pdbe.org/1dwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dwo RCSB], [https://www.ebi.ac.uk/pdbsum/1dwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dwo ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dwo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dwo OCA], [https://pdbe.org/1dwo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dwo RCSB], [https://www.ebi.ac.uk/pdbsum/1dwo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dwo ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HNL_MANES HNL_MANES] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Cassava]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Manihot esculenta]] |
| - | [[Category: Effenberger | + | [[Category: Effenberger F]] |
| - | [[Category: Forster | + | [[Category: Forster S]] |
| - | [[Category: Lauble | + | [[Category: Lauble H]] |
| - | [[Category: Miehlich | + | [[Category: Miehlich B]] |
| - | [[Category: Wajant | + | [[Category: Wajant H]] |
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| - | + | ||
Current revision
Crystal Structure of Hydroxynitrile Lyase from Manihot esculenta in Complex with Substrates Acetone and Chloroacetone:Implications for the Mechanism of Cyanogenesis
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