This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1e9e

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:48, 9 May 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='1e9e' size='340' side='right'caption='[[1e9e]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='1e9e' size='340' side='right'caption='[[1e9e]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1e9e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9E OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1E9E FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1e9e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1E9E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1E9E FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1e2d|1e2d]], [[1e2e|1e2e]], [[1e2f|1e2f]], [[1e2g|1e2g]], [[1e2q|1e2q]], [[1e98|1e98]], [[1e99|1e99]], [[1e9a|1e9a]], [[1e9b|1e9b]], [[1e9c|1e9c]], [[1e9d|1e9d]], [[1e9f|1e9f]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TMP:THYMIDINE-5-PHOSPHATE'>TMP</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1e9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9e OCA], [https://pdbe.org/1e9e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1e9e RCSB], [https://www.ebi.ac.uk/pdbsum/1e9e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1e9e ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1e9e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1e9e OCA], [http://pdbe.org/1e9e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1e9e RCSB], [http://www.ebi.ac.uk/pdbsum/1e9e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1e9e ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/KTHY_HUMAN KTHY_HUMAN] Catalyzes the conversion of dTMP to dTDP.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: DTMP kinase]]
+
[[Category: Brundiers R]]
-
[[Category: Brundiers, R]]
+
[[Category: Goody RS]]
-
[[Category: Goody, R S]]
+
[[Category: Konrad M]]
-
[[Category: Konrad, M]]
+
[[Category: Lavie A]]
-
[[Category: Lavie, A]]
+
[[Category: Ostermann N]]
-
[[Category: Ostermann, N]]
+
[[Category: Padiyar S]]
-
[[Category: Padiyar, S]]
+
[[Category: Reintein J]]
-
[[Category: Reintein, J]]
+
[[Category: Schlichting I]]
-
[[Category: Schlichting, I]]
+
[[Category: Veit T]]
-
[[Category: Veit, T]]
+
-
[[Category: P-loop]]
+
-
[[Category: Phosphotransferase]]
+
-
[[Category: Thymidylate kinase]]
+
-
[[Category: Transferase]]
+

Current revision

Mutant human thymidylate kinase (F105Y) complexed with dTMP and ADP

PDB ID 1e9e

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1e9e"
Personal tools