1ut7

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[[Image:1ut7.png|left|200px]]
 
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{{STRUCTURE_1ut7| PDB=1ut7 | SCENE= }}
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==Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors==
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<StructureSection load='1ut7' size='340' side='right'caption='[[1ut7]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ut7]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UT7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UT7 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AU:GOLD+ION'>AU</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ut7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ut7 OCA], [https://pdbe.org/1ut7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ut7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ut7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ut7 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NAC19_ARATH NAC19_ARATH] Transcription factors that bind specifically to the 5'-CATGTG-3' motif.<ref>PMID:15319476</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ut/1ut7_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ut7 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the DNA-binding NAC domain of Arabidopsis ANAC (abscisic-acid-responsive NAC) has been determined by X-ray crystallography to 1.9A resolution (Protein Data Bank codes 1UT4 and 1UT7). This is the first structure determined for a member of the NAC family of plant-specific transcriptional regulators. NAC proteins are characterized by their conserved N-terminal NAC domains that can bind both DNA and other proteins. NAC proteins are involved in developmental processes, including formation of the shoot apical meristem, floral organs and lateral shoots, as well as in plant hormonal control and defence. The NAC domain does not possess a classical helix-turn-helix motif; instead it reveals a new transcription factor fold consisting of a twisted beta-sheet surrounded by a few helical elements. The functional dimer formed by the NAC domain was identified in the structure, which will serve as a structural template for understanding NAC protein function at the molecular level.
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===STRUCTURE OF THE CONSERVED DOMAIN OF ANAC, A MEMBER OF THE NAC FAMILY OF TRANSCRIPTION FACTORS===
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Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors.,Ernst HA, Olsen AN, Larsen S, Lo Leggio L EMBO Rep. 2004 Mar;5(3):297-303. PMID:15083810<ref>PMID:15083810</ref>
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{{ABSTRACT_PUBMED_15083810}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1ut7" style="background-color:#fffaf0;"></div>
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==About this Structure==
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==See Also==
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[[1ut7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UT7 OCA].
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*[[NAC transcription factor|NAC transcription factor]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:015083810</ref><ref group="xtra">PMID:014684901</ref><references group="xtra"/>
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__TOC__
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[[Category: Arabidopsis thaliana]]
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</StructureSection>
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[[Category: Ernst, H A.]]
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[[Category: Larsen, S.]]
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[[Category: Leggio, L Lo.]]
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[[Category: Olsen, A N.]]
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[[Category: Skriver, K.]]
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[[Category: Abscisic acid response]]
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[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Dna binding]]
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[[Category: Large Structures]]
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[[Category: Nac domain]]
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[[Category: Ernst HA]]
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[[Category: Transcription]]
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[[Category: Larsen S]]
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[[Category: Transcription factor]]
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[[Category: Lo Leggio L]]
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[[Category: Transcription regulation]]
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[[Category: Olsen AN]]
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[[Category: Skriver K]]

Current revision

Structure of the conserved domain of ANAC, a member of the NAC family of transcription factors

PDB ID 1ut7

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