1w3s

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:10, 9 May 2024) (edit) (undo)
 
(10 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1w3s.png|left|200px]]
 
-
<!--
+
==The crystal structure of RecO from Deinococcus radiodurans.==
-
The line below this paragraph, containing "STRUCTURE_1w3s", creates the "Structure Box" on the page.
+
<StructureSection load='1w3s' size='340' side='right'caption='[[1w3s]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1w3s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W3S FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1w3s| PDB=1w3s | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w3s OCA], [https://pdbe.org/1w3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w3s RCSB], [https://www.ebi.ac.uk/pdbsum/1w3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w3s ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q9RW50_DEIRA Q9RW50_DEIRA] Involved in DNA repair and RecF pathway recombination (By similarity).[HAMAP-Rule:MF_00201][SAAS:SAAS022572_004_002906]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/1w3s_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w3s ConSurf].
 +
<div style="clear:both"></div>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
The RecFOR pathway has been shown to be essential for DNA repair through the process of homologous recombination in bacteria and, recently, to be important in the recovery of stalled replication forks following UV irradiation. RecO, along with RecR, RecF, RecQ and RecJ, is a principal actor in this fundamental DNA repair pathway. Here we present the three-dimensional structure of a member of the RecO family. The crystal structure of Deinococcus radiodurans RecO (drRecO) reveals possible binding sites for DNA and for the RecO-binding proteins within its three discrete structural regions: an N-terminal oligonucleotide/oligosaccharide-binding domain, a helical bundle and a zinc-finger motif. Furthermore, drRecO was found to form a stable complex with RecR and to bind both single- and double-stranded DNA. Mutational analysis confirmed the existence of multiple DNA-binding sites within the protein.
-
===THE CRYSTAL STRUCTURE OF RECO FROM DEINOCOCCUS RADIODURANS.===
+
Crystal structure and DNA-binding analysis of RecO from Deinococcus radiodurans.,Leiros I, Timmins J, Hall DR, McSweeney S EMBO J. 2005 Mar 9;24(5):906-18. Epub 2005 Feb 17. PMID:15719017<ref>PMID:15719017</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15719017}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 1w3s" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15719017 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_15719017}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Deinococcus radiodurans R1]]
-
1W3S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W3S OCA].
+
[[Category: Large Structures]]
-
 
+
[[Category: Hall DR]]
-
==Reference==
+
[[Category: Leiros I]]
-
Crystal structure and DNA-binding analysis of RecO from Deinococcus radiodurans., Leiros I, Timmins J, Hall DR, McSweeney S, EMBO J. 2005 Mar 9;24(5):906-18. Epub 2005 Feb 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15719017 15719017]
+
[[Category: Leonard GA]]
-
[[Category: Deinococcus radiodurans]]
+
[[Category: McSweeney SM]]
-
[[Category: Single protein]]
+
[[Category: Timmins J]]
-
[[Category: Hall, D R.]]
+
-
[[Category: Leiros, I.]]
+
-
[[Category: Leonard, G A.]]
+
-
[[Category: Mcsweeney, S M.]]
+
-
[[Category: Timmins, J.]]
+
-
[[Category: Cys4 zinc finger]]
+
-
[[Category: Dna repair]]
+
-
[[Category: Ob-fold]]
+
-
[[Category: Reco]]
+
-
[[Category: Sad]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:27:18 2008''
+

Current revision

The crystal structure of RecO from Deinococcus radiodurans.

PDB ID 1w3s

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1w3s"
Personal tools