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2ca5

From Proteopedia

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==MXIH NEEDLE PROTEIN OF SHIGELLA FLEXNERI (MONOMERIC FORM, RESIDUES 1-78)==
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<StructureSection load='2ca5' size='340' side='right' caption='[[2ca5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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==MxiH needle protein of Shigella Flexneri (monomeric form, residues 1- 78)==
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<StructureSection load='2ca5' size='340' side='right'caption='[[2ca5]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ca5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CA5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ca5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Shigella_flexneri Shigella flexneri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CA5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CA5 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ca5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ca5 RCSB], [http://www.ebi.ac.uk/pdbsum/2ca5 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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<table>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ca5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ca5 OCA], [https://pdbe.org/2ca5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ca5 RCSB], [https://www.ebi.ac.uk/pdbsum/2ca5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ca5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MXIH_SHIFL MXIH_SHIFL] Necessary for the secretion of IPA invasins.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca5_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ca/2ca5_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ca5 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2ca5" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Shigella flexneri]]
[[Category: Shigella flexneri]]
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[[Category: Blocker, A J.]]
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[[Category: Blocker AJ]]
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[[Category: Cordes, F S.]]
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[[Category: Cordes FS]]
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[[Category: Deane, J E.]]
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[[Category: Deane JE]]
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[[Category: Johnson, S.]]
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[[Category: Johnson S]]
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[[Category: Kenjale, R.]]
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[[Category: Kenjale R]]
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[[Category: Lea, S M.]]
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[[Category: Lea SM]]
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[[Category: Picking, W D.]]
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[[Category: Picking WD]]
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[[Category: Picking, W L.]]
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[[Category: Picking WL]]
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[[Category: Roversi, P.]]
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[[Category: Roversi P]]
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[[Category: Mxih]]
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[[Category: Needle complex]]
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[[Category: Protein transport]]
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[[Category: Transport protein]]
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[[Category: Type iii secretion system]]
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[[Category: Virulence]]
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Current revision

MxiH needle protein of Shigella Flexneri (monomeric form, residues 1- 78)

PDB ID 2ca5

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