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2izp

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==BIPD - AN INVASION PRTEIN ASSOCIATED WITH THE TYPE-III SECRETION SYSTEM OF BURKHOLDERIA PSEUDOMALLEI.==
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<StructureSection load='2izp' size='340' side='right' caption='[[2izp]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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==BipD - an invasion protein associated with the type-III secretion system of Burkholderia pseudomallei.==
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<StructureSection load='2izp' size='340' side='right'caption='[[2izp]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2izp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pseudomallei"_whitmore_1913 "bacillus pseudomallei" whitmore 1913]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2IZP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2izp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IZP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IZP FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cmq|2cmq]], [[2ixr|2ixr]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2izp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izp OCA], [http://pdbe.org/2izp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2izp RCSB], [http://www.ebi.ac.uk/pdbsum/2izp PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2izp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2izp OCA], [https://pdbe.org/2izp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2izp RCSB], [https://www.ebi.ac.uk/pdbsum/2izp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2izp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BIPD_BURPS BIPD_BURPS]] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.<ref>PMID:12410823</ref> <ref>PMID:15289563</ref>
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[https://www.uniprot.org/uniprot/BIPD_BURPS BIPD_BURPS] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.<ref>PMID:12410823</ref> <ref>PMID:15289563</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izp_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iz/2izp_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus pseudomallei whitmore 1913]]
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[[Category: Burkholderia pseudomallei]]
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[[Category: Cooper, J B]]
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[[Category: Large Structures]]
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[[Category: Erskine, P T]]
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[[Category: Cooper JB]]
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[[Category: Fox, G C]]
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[[Category: Erskine PT]]
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[[Category: Gill, R]]
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[[Category: Fox GC]]
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[[Category: Knight, M J]]
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[[Category: Gill R]]
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[[Category: Mikolajek, H]]
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[[Category: Knight MJ]]
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[[Category: Ruaux, A]]
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[[Category: Mikolajek H]]
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[[Category: Withers, J]]
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[[Category: Ruaux A]]
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[[Category: Wong-Fat-Sang, N]]
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[[Category: Withers J]]
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[[Category: Wood, M]]
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[[Category: Wong-Fat-Sang N]]
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[[Category: Wood, S P]]
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[[Category: Wood M]]
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[[Category: Invasion protein]]
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[[Category: Wood SP]]
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[[Category: Toxin]]
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[[Category: Type-iii secretion system]]
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[[Category: Virulence factor]]
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Current revision

BipD - an invasion protein associated with the type-III secretion system of Burkholderia pseudomallei.

PDB ID 2izp

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OCA

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