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2j4h

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==CRYSTAL STRUCTURE OF A H121A ESCHERICHIA COLI DCTP DEAMINASE MUTANT ENZYME==
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<StructureSection load='2j4h' size='340' side='right' caption='[[2j4h]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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==Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme==
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<StructureSection load='2j4h' size='340' side='right'caption='[[2j4h]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2j4h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2J4H FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2j4h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J4H FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YYY:DEOXYCYTIDINE+DIPHOSPHATE'>YYY</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xs1|1xs1]], [[1xs4|1xs4]], [[1xs6|1xs6]], [[2j4q|2j4q]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=YYY:DEOXYCYTIDINE+DIPHOSPHATE'>YYY</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dCTP_deaminase dCTP deaminase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.4.13 3.5.4.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j4h OCA], [https://pdbe.org/2j4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j4h RCSB], [https://www.ebi.ac.uk/pdbsum/2j4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j4h ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j4h OCA], [http://pdbe.org/2j4h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2j4h RCSB], [http://www.ebi.ac.uk/pdbsum/2j4h PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DCD_ECOLI DCD_ECOLI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/2j4h_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/2j4h_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Deaminase|Deaminase]]
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*[[Deaminase 3D structures|Deaminase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: DCTP deaminase]]
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[[Category: Large Structures]]
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[[Category: Bynck, J H]]
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[[Category: Bynck JH]]
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[[Category: Fanoe, M]]
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[[Category: Fanoe M]]
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[[Category: Johansson, E]]
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[[Category: Johansson E]]
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[[Category: Larsen, S]]
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[[Category: Larsen S]]
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[[Category: Thymark, M]]
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[[Category: Thymark M]]
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[[Category: Willemoes, M]]
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[[Category: Willemoes M]]
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[[Category: Dctp deaminase]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide metabolism]]
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[[Category: Trimer]]
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Current revision

Crystal structure of a H121A Escherichia coli dCTP deaminase mutant enzyme

PDB ID 2j4h

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