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2j9t
From Proteopedia
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<StructureSection load='2j9t' size='340' side='right'caption='[[2j9t]], [[Resolution|resolution]] 2.70Å' scene=''> | <StructureSection load='2j9t' size='340' side='right'caption='[[2j9t]], [[Resolution|resolution]] 2.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2j9t]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2j9t]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2cmq 2cmq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J9T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J9T FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BO3:BORIC+ACID'>BO3</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j9t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j9t OCA], [https://pdbe.org/2j9t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j9t RCSB], [https://www.ebi.ac.uk/pdbsum/2j9t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j9t ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BIPD_BURPS BIPD_BURPS] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.<ref>PMID:12410823</ref> <ref>PMID:15289563</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Bacillus pseudomallei whitmore 1913]] | ||
| - | [[Category: Large Structures]] | ||
| - | [[Category: Deane, J E]] | ||
| - | [[Category: Field, T]] | ||
| - | [[Category: Galyov, E]] | ||
| - | [[Category: Johnson, S]] | ||
| - | [[Category: Lea, S M]] | ||
| - | [[Category: Roversi, P]] | ||
| - | [[Category: Bipd]] | ||
[[Category: Burkholderia pseudomallei]] | [[Category: Burkholderia pseudomallei]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Deane JE]] |
| - | [[Category: | + | [[Category: Field T]] |
| - | [[Category: | + | [[Category: Galyov E]] |
| + | [[Category: Johnson S]] | ||
| + | [[Category: Lea SM]] | ||
| + | [[Category: Roversi P]] | ||
Current revision
BipD of Burkholderia Pseudomallei
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