This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2jkf
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Plasmodium falciparum profilin== | ==Plasmodium falciparum profilin== | ||
| - | <StructureSection load='2jkf' size='340' side='right' caption='[[2jkf]], [[Resolution|resolution]] 2.31Å' scene=''> | + | <StructureSection load='2jkf' size='340' side='right'caption='[[2jkf]], [[Resolution|resolution]] 2.31Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2jkf]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2jkf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JKF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JKF FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jkf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jkf OCA], [https://pdbe.org/2jkf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jkf RCSB], [https://www.ebi.ac.uk/pdbsum/2jkf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jkf ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PROF_PLAFX PROF_PLAFX] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.<ref>PMID:19000816</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 28: | Line 28: | ||
</div> | </div> | ||
<div class="pdbe-citations 2jkf" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2jkf" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Profilin 3D Structures|Profilin 3D Structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Plasmodium falciparum]] | [[Category: Plasmodium falciparum]] | ||
| - | [[Category: | + | [[Category: Ganter M]] |
| - | [[Category: | + | [[Category: Kursula I]] |
| - | [[Category: | + | [[Category: Kursula P]] |
| - | [[Category: | + | [[Category: Matuschewski K]] |
| + | [[Category: Panjikar S]] | ||
| + | [[Category: Schueler H]] | ||
Current revision
Plasmodium falciparum profilin
| |||||||||||

