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2jvw
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2jvw.png|left|200px]] | ||
| - | < | + | ==Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117== |
| - | + | <StructureSection load='2jvw' size='340' side='right'caption='[[2jvw]]' scene=''> | |
| - | You may | + | == Structural highlights == |
| - | + | <table><tr><td colspan='2'>[[2jvw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_fischeri_ES114 Aliivibrio fischeri ES114]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JVW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |
| - | -- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jvw OCA], [https://pdbe.org/2jvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jvw RCSB], [https://www.ebi.ac.uk/pdbsum/2jvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jvw ProSAT], [https://www.topsan.org/Proteins/NESGC/2jvw TOPSAN]</span></td></tr> |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DNABP_ALIF1 DNABP_ALIF1] Binds double-stranded DNA (dsDNA).<ref>PMID:21905121</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/2jvw_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jvw ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Protein domain family PF09905 (DUF2132) is a family of small domains of unknown function that are conserved in a wide range of bacteria. Here we describe the solution NMR structure of the 80-residue VF0530 protein from Vibrio fischeri, the first structural representative from this protein domain family. We demonstrate that the structure of VF0530 adopts a unique four-helix motif that shows some similarity to the C-terminal double-stranded DNA (dsDNA) binding domain of RecA, as well as other nucleic acid binding domains. Moreover, gel shift binding data indicate a potential dsDNA binding role for VF0530. Proteins 2011; (c) 2011 Wiley-Liss, Inc. | ||
| - | + | Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.,Aramini JM, Rossi P, Fischer M, Xiao R, Acton TB, Montelione GT Proteins. 2011 Oct;79(10):2988-91. doi: 10.1002/prot.23121. Epub 2011 Aug, 26. PMID:21905121<ref>PMID:21905121</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2jvw" style="background-color:#fffaf0;"></div> | |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: Acton | + | __TOC__ |
| - | [[Category: Aramini | + | </StructureSection> |
| - | [[Category: Baran | + | [[Category: Aliivibrio fischeri ES114]] |
| - | [[Category: Liu | + | [[Category: Large Structures]] |
| - | [[Category: Montelione | + | [[Category: Acton TB]] |
| - | + | [[Category: Aramini JM]] | |
| - | [[Category: Nwosu | + | [[Category: Baran MC]] |
| - | [[Category: Owens | + | [[Category: Liu J]] |
| - | [[Category: Rossi | + | [[Category: Montelione GT]] |
| - | [[Category: Rost | + | [[Category: Nwosu C]] |
| - | [[Category: Swapna | + | [[Category: Owens LA]] |
| - | [[Category: Wang | + | [[Category: Rossi P]] |
| - | [[Category: Xiao | + | [[Category: Rost B]] |
| - | + | [[Category: Swapna GVT]] | |
| - | + | [[Category: Wang D]] | |
| - | + | [[Category: Xiao R]] | |
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Current revision
Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117
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Categories: Aliivibrio fischeri ES114 | Large Structures | Acton TB | Aramini JM | Baran MC | Liu J | Montelione GT | Nwosu C | Owens LA | Rossi P | Rost B | Swapna GVT | Wang D | Xiao R

