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2wal
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2wal.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of human GADD45gamma== | |
| - | + | <StructureSection load='2wal' size='340' side='right'caption='[[2wal]], [[Resolution|resolution]] 2.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2wal]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wal OCA], [https://pdbe.org/2wal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wal RCSB], [https://www.ebi.ac.uk/pdbsum/2wal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wal ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | === | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/GA45G_HUMAN GA45G_HUMAN] Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK. | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wal_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wal ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Bhattacharya | + | [[Category: Large Structures]] |
| - | [[Category: Buessow | + | [[Category: Bhattacharya S]] |
| - | [[Category: Goetz | + | [[Category: Buessow K]] |
| - | [[Category: Heinemann | + | [[Category: Goetz F]] |
| - | [[Category: Mueller | + | [[Category: Heinemann U]] |
| - | [[Category: Quedenau | + | [[Category: Mueller JJ]] |
| - | [[Category: Roske | + | [[Category: Quedenau C]] |
| - | [[Category: Turnbull | + | [[Category: Roske Y]] |
| - | + | [[Category: Turnbull AP]] | |
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Current revision
Crystal Structure of human GADD45gamma
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