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2wbi
From Proteopedia
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==Crystal structure of human acyl-CoA dehydrogenase 11== | ==Crystal structure of human acyl-CoA dehydrogenase 11== | ||
| - | <StructureSection load='2wbi' size='340' side='right' caption='[[2wbi]], [[Resolution|resolution]] 2.80Å' scene=''> | + | <StructureSection load='2wbi' size='340' side='right'caption='[[2wbi]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wbi]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2wbi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WBI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WBI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wbi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wbi OCA], [https://pdbe.org/2wbi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wbi RCSB], [https://www.ebi.ac.uk/pdbsum/2wbi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wbi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACD11_HUMAN ACD11_HUMAN] Acyl-CoA dehydrogenase, that exhibits maximal activity towards saturated C22-CoA (PubMed:21237683). Probably participates in beta-oxydation and energy production but could also play a role in the metabolism of specific fatty acids to control fatty acids composition of cellular lipids in brain (Probable).<ref>PMID:21237683</ref> <ref>PMID:21237683</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wbi ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wbi ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Acyl-CoA dehydrogenase 3D structures|Acyl-CoA dehydrogenase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Guo | + | [[Category: Guo K]] |
| - | [[Category: Muniz | + | [[Category: Muniz JRC]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | [[Category: Pilka | + | [[Category: Pilka E]] |
| - | [[Category: Roos | + | [[Category: Roos A]] |
| - | [[Category: Savitsky | + | [[Category: Savitsky P]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Yue | + | [[Category: Yue W]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
| - | + | ||
| - | + | ||
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Current revision
Crystal structure of human acyl-CoA dehydrogenase 11
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Edwards AM | Guo K | Muniz JRC | Oppermann U | Pilka E | Roos A | Savitsky P | Weigelt J | Yue W | Von Delft F
