This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2wpv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:16, 9 May 2024) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
-
==CRYSTAL STRUCTURE OF S. CEREVISIAE GET4-GET5 COMPLEX==
+
 
-
<StructureSection load='2wpv' size='340' side='right' caption='[[2wpv]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
+
==Crystal structure of S. cerevisiae Get4-Get5 complex==
 +
<StructureSection load='2wpv' size='340' side='right'caption='[[2wpv]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2wpv]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WPV FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2wpv]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WPV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WPV FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpv OCA], [http://pdbe.org/2wpv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wpv RCSB], [http://www.ebi.ac.uk/pdbsum/2wpv PDBsum]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wpv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wpv OCA], [https://pdbe.org/2wpv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wpv RCSB], [https://www.ebi.ac.uk/pdbsum/2wpv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wpv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GET4_YEAST GET4_YEAST]] May play a role in insertion of tail-anchored proteins into the endoplasmic reticulum membrane.<ref>PMID:19325107</ref> [[http://www.uniprot.org/uniprot/MDY2_YEAST MDY2_YEAST]] Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos.<ref>PMID:10514570</ref> <ref>PMID:16390866</ref>
+
[https://www.uniprot.org/uniprot/MDY2_YEAST MDY2_YEAST] Required for efficient mating. Involved in the production of alpha-factor, the KAR9 and TUB1 location to the shmoo tip and nuclear migration into pheromone-induced shmoos.<ref>PMID:10514570</ref> <ref>PMID:16390866</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wpv_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wp/2wpv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 31: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 18824]]
+
[[Category: Large Structures]]
-
[[Category: Chang, Y W]]
+
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Cheng, M Y]]
+
[[Category: Chang Y-W]]
-
[[Category: Chuang, Y C]]
+
[[Category: Cheng M-Y]]
-
[[Category: Ho, Y C]]
+
[[Category: Chuang Y-C]]
-
[[Category: Hsiao, C D]]
+
[[Category: Ho Y-C]]
-
[[Category: Sun, Y J]]
+
[[Category: Hsiao C-D]]
-
[[Category: Wang, C]]
+
[[Category: Sun Y-J]]
-
[[Category: Get4]]
+
[[Category: Wang C]]
-
[[Category: Get5]]
+
-
[[Category: Golgi-er trafficking]]
+
-
[[Category: Protein binding]]
+
-
[[Category: Tail-anchored protein]]
+

Current revision

Crystal structure of S. cerevisiae Get4-Get5 complex

PDB ID 2wpv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2wpv"
Personal tools