This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ww9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:18, 9 May 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
==CRYO-EM STRUCTURE OF THE ACTIVE YEAST SSH1 COMPLEX BOUND TO THE YEAST 80S RIBOSOME==
+
 
-
<StructureSection load='2ww9' size='340' side='right' caption='[[2ww9]], [[Resolution|resolution]] 8.60&Aring;' scene=''>
+
==Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome==
 +
<SX load='2ww9' size='340' side='right' viewer='molstar' caption='[[2ww9]], [[Resolution|resolution]] 8.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2ww9]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WW9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WW9 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2ww9]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WW9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WW9 FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k5y|1k5y]], [[1s1i|1s1i]], [[2wwa|2wwa]], [[2wwb|2wwb]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.6&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ww9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ww9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ww9 RCSB], [http://www.ebi.ac.uk/pdbsum/2ww9 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ww9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ww9 OCA], [https://pdbe.org/2ww9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ww9 RCSB], [https://www.ebi.ac.uk/pdbsum/2ww9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ww9 ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SC6B2_YEAST SC6B2_YEAST] Part of the Ssh1 complex, which probably is the major component of a channel-forming translocon complex that may function exclusively in the cotranslational pathway of protein endoplasmic reticulum (ER) import.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2ww9_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2ww9_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ww9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 24: Line 27:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2ww9" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
Line 37: Line 41:
<references/>
<references/>
__TOC__
__TOC__
-
</StructureSection>
+
</SX>
 +
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
-
[[Category: Armache, J P.]]
+
[[Category: Armache JP]]
-
[[Category: Becker, T.]]
+
[[Category: Becker T]]
-
[[Category: Beckmann, R.]]
+
[[Category: Beckmann R]]
-
[[Category: Berninghausen, O.]]
+
[[Category: Berninghausen O]]
-
[[Category: Bhushan, S.]]
+
[[Category: Bhushan S]]
-
[[Category: Funes, S.]]
+
[[Category: Funes S]]
-
[[Category: Gilmore, R.]]
+
[[Category: Gilmore R]]
-
[[Category: Gumbart, J.]]
+
[[Category: Gumbart J]]
-
[[Category: Jarasch, A.]]
+
[[Category: Jarasch A]]
-
[[Category: Jossinet, F.]]
+
[[Category: Jossinet F]]
-
[[Category: Mandon, E.]]
+
[[Category: Mandon E]]
-
[[Category: Mielke, T.]]
+
[[Category: Mielke T]]
-
[[Category: Schulten, K.]]
+
[[Category: Schulten K]]
-
[[Category: Westhof, E.]]
+
[[Category: Westhof E]]
-
[[Category: Cotranslational protein translocation]]
+
-
[[Category: Endoplasmic reticulum]]
+
-
[[Category: Isopeptide bond]]
+
-
[[Category: Membrane]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Protein conducting channel]]
+
-
[[Category: Protein exit tunnel]]
+
-
[[Category: Protein transport]]
+
-
[[Category: Ribonucleoprotein]]
+
-
[[Category: Ribosomal protein]]
+
-
[[Category: Ribosome]]
+
-
[[Category: Rna-binding]]
+
-
[[Category: Rrna-binding]]
+
-
[[Category: Signal sequence]]
+
-
[[Category: Translocation]]
+
-
[[Category: Transmembrane]]
+
-
[[Category: Transport]]
+

Current revision

Cryo-EM structure of the active yeast Ssh1 complex bound to the yeast 80S ribosome

2ww9, resolution 8.60Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools