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2wwb

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==CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME==
==CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME==
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<StructureSection load='2wwb' size='340' side='right' caption='[[2wwb]], [[Resolution|resolution]] 6.48&Aring;' scene=''>
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<SX load='2wwb' size='340' side='right' viewer='molstar' caption='[[2wwb]], [[Resolution|resolution]] 6.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wwb]] is a 15 chain structure with sequence from [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris] and [http://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WWB FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wwb]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris] and [https://en.wikipedia.org/wiki/Triticum_aestivum Triticum aestivum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WWB FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1k5y|1k5y]], [[1s1i|1s1i]], [[2wwa|2wwa]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.48&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wwb RCSB], [http://www.ebi.ac.uk/pdbsum/2wwb PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wwb OCA], [https://pdbe.org/2wwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wwb RCSB], [https://www.ebi.ac.uk/pdbsum/2wwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wwb ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/S61A1_CANLF S61A1_CANLF]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2wwb_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ww/2wwb_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wwb ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2wwb" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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<references/>
<references/>
__TOC__
__TOC__
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</StructureSection>
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</SX>
[[Category: Canis lupus familiaris]]
[[Category: Canis lupus familiaris]]
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[[Category: Large Structures]]
[[Category: Triticum aestivum]]
[[Category: Triticum aestivum]]
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[[Category: Armache, J P]]
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[[Category: Armache JP]]
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[[Category: Becker, T]]
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[[Category: Becker T]]
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[[Category: Beckmann, R]]
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[[Category: Beckmann R]]
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[[Category: Berninghausen, O]]
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[[Category: Berninghausen O]]
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[[Category: Bhushan, S]]
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[[Category: Bhushan S]]
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[[Category: Funes, S]]
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[[Category: Funes S]]
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[[Category: Gilmore, R]]
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[[Category: Gilmore R]]
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[[Category: Gumbart, J]]
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[[Category: Gumbart J]]
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[[Category: Jarasch, A]]
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[[Category: Jarasch A]]
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[[Category: Jossinet, F]]
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[[Category: Jossinet F]]
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[[Category: Mandon, E]]
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[[Category: Mandon E]]
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[[Category: Mielke, T]]
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[[Category: Mielke T]]
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[[Category: Schulten, K]]
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[[Category: Schulten K]]
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[[Category: Westhof, E]]
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[[Category: Westhof E]]
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[[Category: Cotranslational protein translocation]]
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[[Category: Protein conducting channel]]
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[[Category: Protein exit tunnel]]
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[[Category: Ribosome]]
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[[Category: Signal sequence]]
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Current revision

CRYO-EM STRUCTURE OF THE MAMMALIAN SEC61 COMPLEX BOUND TO THE ACTIVELY TRANSLATING WHEAT GERM 80S RIBOSOME

2wwb, resolution 6.48Å

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