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2xgm

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==SUBSTRATE AND PRODUCT ANALOGUES AS HUMAN O-GLCNAC TRANSFERASE INHIBITORS.==
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==Substrate and product analogues as human O-GlcNAc transferase inhibitors.==
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<StructureSection load='2xgm' size='340' side='right' caption='[[2xgm]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
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<StructureSection load='2xgm' size='340' side='right'caption='[[2xgm]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xgm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_campestris"_pammel_1895 "bacillus campestris" pammel 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XGM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XGM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xgm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_campestris Xanthomonas campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XGM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XGM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LXN:ALLOXAN'>LXN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vsy|2vsy]], [[2xgo|2xgo]], [[2xgs|2xgs]], [[2jlb|2jlb]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LXN:ALLOXAN'>LXN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xgm OCA], [http://pdbe.org/2xgm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xgm RCSB], [http://www.ebi.ac.uk/pdbsum/2xgm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xgm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xgm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xgm OCA], [https://pdbe.org/2xgm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xgm RCSB], [https://www.ebi.ac.uk/pdbsum/2xgm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xgm ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8PC69_XANCP Q8PC69_XANCP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/2xgm_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/2xgm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[O-GlcNAc transferase|O-GlcNAc transferase]]
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*[[O-GlcNAc transferase 3D structures|O-GlcNAc transferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus campestris pammel 1895]]
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[[Category: Large Structures]]
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[[Category: Aalten, D M.Van]]
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[[Category: Xanthomonas campestris]]
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[[Category: Blair, D E]]
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[[Category: Blair DE]]
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[[Category: Borodkin, V S]]
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[[Category: Borodkin VS]]
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[[Category: Dorfmueller, H C]]
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[[Category: Dorfmueller HC]]
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[[Category: Navratilova, I]]
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[[Category: Navratilova I]]
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[[Category: Pathak, S]]
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[[Category: Pathak S]]
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[[Category: Transferase]]
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[[Category: Van Aalten DM]]

Current revision

Substrate and product analogues as human O-GlcNAc transferase inhibitors.

PDB ID 2xgm

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