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4b24

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<StructureSection load='4b24' size='340' side='right'caption='[[4b24]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4b24' size='340' side='right'caption='[[4b24]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b24]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Cbs_356 Cbs 356]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B24 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B24 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b24]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B24 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B24 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4b21|4b21]], [[4b22|4b22]], [[4b23|4b23]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-3-methyladenine_glycosylase_II DNA-3-methyladenine glycosylase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.2.21 3.2.2.21] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b24 OCA], [https://pdbe.org/4b24 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b24 RCSB], [https://www.ebi.ac.uk/pdbsum/4b24 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b24 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b24 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b24 OCA], [http://pdbe.org/4b24 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b24 RCSB], [http://www.ebi.ac.uk/pdbsum/4b24 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b24 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MAG2_SCHPO MAG2_SCHPO]] Invlved in base excision repair of methyl methanesulfonate-damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions.<ref>PMID:18270439</ref>
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[https://www.uniprot.org/uniprot/MAG2_SCHPO MAG2_SCHPO] Invlved in base excision repair of methyl methanesulfonate-damaged DNA by hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions.<ref>PMID:18270439</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cbs 356]]
 
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[[Category: DNA-3-methyladenine glycosylase II]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Alseth, I]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Bjoras, M]]
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[[Category: Synthetic construct]]
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[[Category: Dalhus, B]]
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[[Category: Alseth I]]
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[[Category: Forstrom, R J]]
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[[Category: Bjoras M]]
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[[Category: Huffman, J]]
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[[Category: Dalhus B]]
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[[Category: Korvald, H]]
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[[Category: Forstrom RJ]]
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[[Category: McMurray, C T]]
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[[Category: Huffman J]]
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[[Category: Nilsen, L]]
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[[Category: Korvald H]]
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[[Category: Tainer, J A]]
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[[Category: McMurray CT]]
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[[Category: Helix-hairpin-helix]]
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[[Category: Nilsen L]]
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[[Category: Hydrolase-dna complex]]
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[[Category: Tainer JA]]

Current revision

Unprecedented sculpting of DNA at abasic sites by DNA glycosylase homolog Mag2

PDB ID 4b24

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