4c7h
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Leismania major N-myristoyltransferase in complex with a peptidomimetic (-NH2) molecule== | ==Leismania major N-myristoyltransferase in complex with a peptidomimetic (-NH2) molecule== | ||
| - | <StructureSection load='4c7h' size='340' side='right' caption='[[4c7h]], [[Resolution|resolution]] 1.40Å' scene=''> | + | <StructureSection load='4c7h' size='340' side='right'caption='[[4c7h]], [[Resolution|resolution]] 1.40Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4c7h]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C7H OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[4c7h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4C7H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4C7H FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EN5:N-(10-AMINODECANOYL)-L-SERYL-N-(2-CYCLOHEXYLETHYL)-L-LYSINAMIDE'>EN5</scene>, <scene name='pdbligand=ENF:N-{(5E)-10-[(9E)-TETRADEC-9-ENOYLAMINO]DEC-5-ENOYL}-L-SERYL-N-(2-CYCLOHEXYLETHYL)-L-LYSINAMIDE'>ENF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EN5:N-(10-AMINODECANOYL)-L-SERYL-N-(2-CYCLOHEXYLETHYL)-L-LYSINAMIDE'>EN5</scene>, <scene name='pdbligand=ENF:N-{(5E)-10-[(9E)-TETRADEC-9-ENOYLAMINO]DEC-5-ENOYL}-L-SERYL-N-(2-CYCLOHEXYLETHYL)-L-LYSINAMIDE'>ENF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MYA:TETRADECANOYL-COA'>MYA</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4c7h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4c7h OCA], [https://pdbe.org/4c7h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4c7h RCSB], [https://www.ebi.ac.uk/pdbsum/4c7h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4c7h ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q4Q5S8_LEIMA Q4Q5S8_LEIMA] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity). | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4c7h" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Brannigan | + | [[Category: Leishmania major]] |
| - | [[Category: Goncalves | + | [[Category: Brannigan JA]] |
| - | [[Category: Leatherbarrow | + | [[Category: Goncalves V]] |
| - | [[Category: Olaleye | + | [[Category: Leatherbarrow RJ]] |
| - | [[Category: Roberts | + | [[Category: Olaleye TO]] |
| - | [[Category: Tate | + | [[Category: Roberts SM]] |
| - | [[Category: Wilkinson | + | [[Category: Tate EW]] |
| - | + | [[Category: Wilkinson AJ]] | |
| - | + | ||
Current revision
Leismania major N-myristoyltransferase in complex with a peptidomimetic (-NH2) molecule
| |||||||||||
